Managing disorders of consciousness: the role of electroencephalography

Y Bai, Y Lin, U Ziemann - Journal of neurology, 2021 - Springer
Disorders of consciousness (DOC) are an important but still underexplored entity in
neurology. Novel electroencephalography (EEG) measures are currently being employed …

[HTML][HTML] Whole-brain models to explore altered states of consciousness from the bottom up

R Cofré, R Herzog, PAM Mediano, J Piccinini… - Brain Sciences, 2020 - mdpi.com
The scope of human consciousness includes states departing from what most of us
experience as ordinary wakefulness. These altered states of consciousness constitute a …

Deep brain stimulation of the thalamus restores signatures of consciousness in a nonhuman primate model

J Tasserie, L Uhrig, JD Sitt, D Manasova, M Dupont… - Science …, 2022 - science.org
Loss of consciousness is associated with the disruption of long-range thalamocortical and
corticocortical brain communication. We tested the hypothesis that deep brain stimulation …

Proceedings of the first curing coma campaign NIH symposium: challenging the future of research for coma and disorders of consciousness

J Claassen, Y Akbari, S Alexander, MK Bader, K Bell… - Neurocritical care, 2021 - Springer
Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden
for patients, families, and society worldwide. As part of the Curing Coma Campaign, the …

Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness

Y Sanz Perl, C Pallavicini, I Pérez Ipiña… - PLoS computational …, 2021 - journals.plos.org
Consciousness transiently fades away during deep sleep, more stably under anesthesia,
and sometimes permanently due to brain injury. The development of an index to quantify the …

Low-dimensional organization of global brain states of reduced consciousness

YS Perl, C Pallavicini, J Piccinini, A Demertzi… - Cell Reports, 2023 - cell.com
Brain states are frequently represented using a unidimensional scale measuring the
richness of subjective experience (level of consciousness). This description assumes a …

Cerebral electrometabolic coupling in disordered and normal states of consciousness

J Annen, G Frasso, GJM van der Lande, EAC Bonin… - Cell reports, 2023 - cell.com
We assess cerebral integrity with cortical and subcortical FDG-PET and cortical
electroencephalography (EEG) within the mesocircuit model framework in patients with …

[HTML][HTML] Advances in stroke neurorehabilitation

ME Gunduz, B Bucak, Z Keser - Journal of clinical medicine, 2023 - mdpi.com
Stroke is one of the leading causes of disability worldwide despite recent advances in
hyperacute interventions to lessen the initial impact of stroke. Stroke recovery therapies are …

Brain-scale cortico-cortical functional connectivity in the delta-theta band is a robust signature of conscious states: an intracranial and scalp EEG study

P Bourdillon, B Hermann, M Guénot, H Bastuji… - Scientific Reports, 2020 - nature.com
Long-range cortico-cortical functional connectivity has long been theorized to be necessary
for conscious states. In the present work, we estimate long-range cortical connectivity in a …

[HTML][HTML] Multimodal FDG-PET and EEG assessment improves diagnosis and prognostication of disorders of consciousness

B Hermann, J Stender, MO Habert, A Kas… - NeuroImage: Clinical, 2021 - Elsevier
Introduction Functional brain-imaging techniques have revealed that clinical examination of
disorders of consciousness (DoC) can underestimate the conscious level of patients. FDG …