Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

To maintain the stability and integrity of cellular genomic DNA, DNA repair enzymes catalyze
the repair of DNA damage caused by exogenous and endogenous factors through various …

Abstract All chemotherapeutic treatments worldwide (> 50%) use platinum‐based
compounds. Despite their clinical success, an increasing number of platinum drug‐resistant …

Cancer diagnosis and therapeutics (theranostics) based on the tumor microenvironment
(TME) and biomarkers has been an emerging approach for precision medicine. DNA …

DNA‐based nanodevices equipped with localized modules have been promising probes for
biomarker detection. Such devices heavily rely on the intramolecular hybridization reaction …

The dynamic variation of the expression profile and spatial landscape of multiple enzymes
are crucial factors influencing tumor progression and drug treatment. However, the …

Catalytic DNA circuits represent a versatile toolbox for tracking intracellular biomarkers yet
are constrained with low anti-interference capacity originating from their severe off-site …

Catalytic DNA circuit, a versatile synthetic molecular nanodevice, shows great potential for in
vivo bioimaging application, yet is distorted by its off-site signal leakage. The endogenously …

DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

Accurate cancer cell identification and efficient therapy are extremely desirable and
challenging in clinics. Here, we reported the first example of DNA tetrahedron …