Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has currently led to a global pandemic with …

Heart failure causes significant morbidity and mortality worldwide. The underlying
mechanisms and pathological changes associated with heart failure are exceptionally …

Cardiovascular and heart diseases are leading causes of morbidity and mortality. Coronary
artery endothelial and vascular dysfunction, inflammation, and mitochondrial dysfunction …

Endotoxemia elicits a multiorgan inflammatory response that results in cardiac dysfunction
and often leads to death. Inflammation-induced metabolism of endogenous N-3 and N-6 …

High rates of cardiac fatty acid oxidation during reperfusion of ischemic hearts contribute to
contractile dysfunction. This study aimed to investigate whether lysine acetylation affects …

Abstract Background Mitochondrial ROS (mtROS) accumulation and NLRP3 inflammasome
activation are critical in the pathogenesis of myocardial ischemia-reperfusion injury (MIRI) …

Epoxide metabolites from n-3 and n-6 polyunsaturated fatty acids arouse interest thanks to
their physiological and pharmacological activities. Their chemical synthesis has significant …

ABSTRACT Introduction Cytochrome P450s (CYPs) are a superfamily of monooxygenases
with diverse biological roles. CYP2J2 is an isozyme highly expressed in the heart where it …

Implant surgery is followed by a series of inflammatory reactions that directly affect its
postoperative results. The inflammasome plays a vital role in the inflammatory response by …

Aims Although current clinical therapies following myocardial infarction have improved
patient outcomes, morbidity, and mortality rates secondary to ischemic and ischemia …