The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …

Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …

Aims The mechanisms underlying persistent atrial fibrillation (AF) in patients with atrial
fibrosis are poorly understood. The goal of this study was to use patient-derived atrial …

This book covers the main mathematical and numerical models in computational
electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to …

Models of cardiac tissue electrophysiology are an important component of the Cardiac
Physiome Project, which is an international effort to build biophysically based multi-scale …

Recent developments in cardiac simulation have rendered the heart the most highly
integrated example of a virtual organ. We are on the brink of a revolution in cardiac …

A bidomain reaction-diffusion model of the human heart was developed, and potentials
resulting from normal depolarization and repolarization were compared with results from a …

Ongoing developments in cardiac modelling have resulted, in particular, in the development
of advanced and increasingly complex computational frameworks for simulating cardiac …

The bidomain equations are widely used for the simulation of electrical activity in cardiac
tissue. They are especially important for accurately modeling extracellular stimulation, as …