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Robust evidence for bats as reservoir hosts is lacking in most African virus studies: a review and call to optimize sampling and conserve bats
Africa experiences frequent emerging disease outbreaks among humans, with bats often
proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings …
proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings …
Approaches and challenges to inferring the geographical source of infectious disease outbreaks using genomic data
Genomic data hold increasing potential in the elucidation of transmission dynamics and
geographical sources of infectious disease outbreaks. Phylogeographic methods that use …
geographical sources of infectious disease outbreaks. Phylogeographic methods that use …
Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks
Seven years after the declaration of the first epidemic of Ebola virus disease in Guinea, the
country faced a new outbreak—between 14 February and 19 June 2021—near the …
country faced a new outbreak—between 14 February and 19 June 2021—near the …
A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates
R Hunegnaw, AN Honko, L Wang, D Carr… - Science translational …, 2022 - science.org
Marburg virus (MARV) causes a severe hemorrhagic fever disease in primates with mortality
rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent …
rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent …
National Monkeypox Surveillance, Central African Republic, 2001–2021
C Besombes, F Mbrenga, L Schaeffer… - Emerging infectious …, 2022 - pmc.ncbi.nlm.nih.gov
We analyzed monkeypox disease surveillance in Central African Republic (CAR) during
2001–2021. Surveillance data show 95 suspected outbreaks, 40 of which were confirmed as …
2001–2021. Surveillance data show 95 suspected outbreaks, 40 of which were confirmed as …
Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors
J Liu, JC Trefry, AM Babka, CW Schellhase… - Science translational …, 2022 - science.org
Effective therapeutics have been developed against acute Ebola virus disease (EVD) in both
humans and experimentally infected nonhuman primates. However, the risk of viral …
humans and experimentally infected nonhuman primates. However, the risk of viral …
Effectiveness of rVSV-ZEBOV vaccination during the 2018–20 Ebola virus disease epidemic in the Democratic Republic of the Congo: a retrospective test-negative …
Background The recombinant vesicular stomatitis virus–Zaire Ebola virus (rVSV-ZEBOV)
vaccine is the only WHO prequalified vaccine recommended for use to respond to outbreaks …
vaccine is the only WHO prequalified vaccine recommended for use to respond to outbreaks …
Chapare hemorrhagic fever and virus detection in rodents in Bolivia in 2019
R Loayza Mafayle, ME Morales-Betoulle… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background In June 2019, the Bolivian Ministry of Health reported a cluster of cases
of hemorrhagic fever that started in the municipality of Caranavi and expanded to La Paz …
of hemorrhagic fever that started in the municipality of Caranavi and expanded to La Paz …
The multiple origins of ebola disease outbreaks
Abstract Background The origins of Ebola disease outbreaks remain enigmatic. Historically
outbreaks have been attributed to spillover events from wildlife. However, recent data …
outbreaks have been attributed to spillover events from wildlife. However, recent data …
The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections
MR Hickman, DL Saunders, CA Bigger… - PLoS neglected …, 2022 - journals.plos.org
The Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear
Defense (JPEO-CBRND) began development of a broad-spectrum antiviral countermeasure …
Defense (JPEO-CBRND) began development of a broad-spectrum antiviral countermeasure …