Wound healing is a complex process that can be divided into at least 3 continuous and
overlap** processes: an inflammatory reaction, a proliferative process leading to tissue …

During wound healing, angiogenic capillary sprouts invade the fibrin/fibronectin-rich wound
clot and within a few days organize into a microvascular network throughout the granulation …

Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates, with simplified
processing and without biochemical blood handling. In this fourth article, investigation is …

Fibrinogen and fibrin play an important role in blood clotting, fibrinolysis, cellular and matrix
interactions, inflammation, wound healing, angiogenesis, and neoplasia. The contribution of …

Angiogenesis is critical to wound repair. Newly formed blood vessels participate in
provisional granulation tissue formation and provide nutrition and oxygen to growing tissues …

Although hemostasis is the major role of fibrin in wound repair, once the clot is present the
wound cells must deal with it. The invasion and clearing of fibrin by these cells involves …

Fibrinogen is one of the primary components of the coagulation cascade and rapidly forms
an insoluble matrix following tissue injury. In addition to its important role in hemostasis …

Cancer cells are able to proliferate at accelerated rates within the confines of a three-
dimensional (3D) extracellular matrix (ECM) that is rich in type I collagen. The mechanisms …

Gingival recession is defined as the displacement and destruction of the soft tissue margin
apical to the cementoenamel junction (CEJ). Obtaining predictable root coverage supported …

Fibrin glue has been widely used as an adhesive in plastic and reconstructive surgery. This
article reviews the advantages and disadvantages of its use with skin grafts and tissue …