Revisiting the stress concept: implications for affective disorders
BS McEwen, H Akil - Journal of Neuroscience, 2020 - Soc Neuroscience
Over the last 50 years, the concept of stress has evolved significantly, and our
understanding of the underlying neurobiology has expanded dramatically. Rather than …
understanding of the underlying neurobiology has expanded dramatically. Rather than …
Treatment resistant depression: a multi-scale, systems biology approach
An estimated 50% of depressed patients are inadequately treated by available interventions.
Even with an eventual recovery, many patients require a trial and error approach, as there …
Even with an eventual recovery, many patients require a trial and error approach, as there …
Sex-specific transcriptional signatures in human depression
Major depressive disorder (MDD) is a leading cause of disease burden worldwide. While the
incidence, symptoms and treatment of MDD all point toward major sex differences, the …
incidence, symptoms and treatment of MDD all point toward major sex differences, the …
Microbiota modulation counteracts Alzheimer's disease progression influencing neuronal proteolysis and gut hormones plasma levels
L Bonfili, V Cecarini, S Berardi, S Scarpona… - Scientific reports, 2017 - nature.com
Gut microbiota has a proven role in regulating multiple neuro-chemical pathways through
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …
the highly interconnected gut-brain axis. Oral bacteriotherapy thus has potential in the …
Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression
Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …
burden in western societies. It is associated with atrophy and impaired functioning of cortico …
Astrocyte pathology in major depressive disorder: insights from human postmortem brain tissue
G Rajkowska, CA Stockmeier - Current drug targets, 2013 - ingentaconnect.com
The present paper reviews astrocyte pathology in major depressive disorder (MDD) and
proposes that reductions in astrocytes and related markers are key features in the pathology …
proposes that reductions in astrocytes and related markers are key features in the pathology …
The FGF family: biology, pathophysiology and therapy
A Beenken, M Mohammadi - Nature reviews Drug discovery, 2009 - nature.com
The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …
processes, including brain patterning, branching morphogenesis and limb development …
A neurotrophic model for stress-related mood disorders
There is a growing body of evidence demonstrating that stress decreases the expression of
brain-derived neurotrophic factor (BDNF) in limbic structures that control mood and that …
brain-derived neurotrophic factor (BDNF) in limbic structures that control mood and that …
[LIVRE][B] The Social Neuroscience of Education: Optimizing Attachment and Learning in the Classroom
L Cozolino - 2013 - books.google.com
Creating a healthy, social classroom environment. This book explains how the brain, as a
social organism, learns best throughout the lifespan, from our early schooling through late …
social organism, learns best throughout the lifespan, from our early schooling through late …
Molecular mechanisms of depression: perspectives on new treatment strategies
Depression is a multicausal disorder and has been associated with the risk to develop
cancer, dementia, diabetes, epilepsy and stroke. As a metabolic disorder depression has …
cancer, dementia, diabetes, epilepsy and stroke. As a metabolic disorder depression has …