The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Lower brain glucose metabolism in normal ageing is predominantly frontal and temporal: A systematic review and pooled effect size and activation likelihood …

HA Deery, R Di Paolo, C Moran, GF Egan… - Human Brain …, 2023 - Wiley Online Library
This review provides a qualitative and quantitative analysis of cerebral glucose metabolism
in ageing. We undertook a systematic literature review followed by pooled effect size and …

Functional PET/MRI reveals active inhibition of neuronal activity during optogenetic activation of the nigrostriatal pathway

S Haas, F Bravo, TM Ionescu… - Science …, 2024 - science.org
The dopaminergic system is a central component of the brain's neurobiological framework,
governing motor control and reward responses and playing an essential role in various …

Towards lower-dose PET using physics-based uncertainty-aware multimodal learning with robustness to out-of-distribution data

VP Sudarshan, U Upadhyay, GF Egan, Z Chen… - Medical Image …, 2021 - Elsevier
Radiation exposure in positron emission tomography (PET) imaging limits its usage in the
studies of radiation-sensitive populations, eg, pregnant women, children, and adults that …

Metabolic and hemodynamic resting-state connectivity of the human brain: a high-temporal resolution simultaneous BOLD-fMRI and FDG-fPET multimodality study

SD Jamadar, PGD Ward, EX Liang, ER Orchard… - Cerebral …, 2021 - academic.oup.com
Abstract Simultaneous [18F]-fluorodeoxyglucose positron emission tomography functional
magnetic resonance imaging (FDG-PET/fMRI) provides the capacity to image 2 sources of …

Brain connectomics: time for a molecular imaging perspective?

A Sala, A Lizarraga, SP Caminiti, VD Calhoun… - Trends in cognitive …, 2023 - cell.com
In the past two decades brain connectomics has evolved into a major concept in
neuroscience. However, the current perspective on brain connectivity and how it underpins …

Simultaneous BOLD-fMRI and constant infusion FDG-PET data of the resting human brain

SD Jamadar, PGD Ward, TG Close, A Fornito… - Scientific data, 2020 - nature.com
Abstract Simultaneous [18 F]-fluorodeoxyglucose positron emission tomography and
functional magnetic resonance imaging (FDG-PET/fMRI) provides the capability to image …

Challenges and perspectives of the hybridization of PET with functional MRI or ultrasound for neuroimaging

N Tournier, C Comtat, V Lebon, JL Gennisson - Neuroscience, 2021 - Elsevier
Hybridization of positron emission tomography (PET) with other functional neuroimaging
techniques such as functional magnetic resonance imaging (fMRI) or functional ultrasound …

The metabolic costs of cognition

SD Jamadar, A Behler, H Deery… - Trends in Cognitive …, 2025 - cell.com
Cognition and behavior are emergent properties of brain systems that seek to maximize
complex and adaptive behaviors while minimizing energy utilization. Different species …

Functional imaging of the exposed brain

S Soloukey, AJPE Vincent, M Smits… - Frontiers in …, 2023 - frontiersin.org
When the brain is exposed, such as after a craniotomy in neurosurgical procedures, we are
provided with the unique opportunity for real-time imaging of brain functionality. Real-time …