Towards a biologically annotated brain connectome

V Bazinet, JY Hansen, B Misic - Nature reviews neuroscience, 2023 - nature.com
The brain is a network of interleaved neural circuits. In modern connectomics, brain
connectivity is typically encoded as a network of nodes and edges, abstracting away the rich …

Localization of the epileptogenic zone using high frequency oscillations

A Thomschewski, AS Hincapié, B Frauscher - Frontiers in neurology, 2019 - frontiersin.org
For patients with drug-resistant focal epilepsy, surgery is the therapy of choice in order to
achieve seizure freedom. Epilepsy surgery foremost requires the identification of the …

Parameterizing neural power spectra into periodic and aperiodic components

T Donoghue, M Haller, EJ Peterson, P Varma… - Nature …, 2020 - nature.com
Electrophysiological signals exhibit both periodic and aperiodic properties. Periodic
oscillations have been linked to numerous physiological, cognitive, behavioral and disease …

Methodological considerations for studying neural oscillations

T Donoghue, N Schaworonkow… - European journal of …, 2022 - Wiley Online Library
Neural oscillations are ubiquitous across recording methodologies and species, broadly
associated with cognitive tasks, and amenable to computational modelling that investigates …

Delineating epileptogenic networks using brain imaging data and personalized modeling in drug-resistant epilepsy

HE Wang, M Woodman, P Triebkorn… - Science Translational …, 2023 - science.org
Precise estimates of epileptogenic zone networks (EZNs) are crucial for planning
intervention strategies to treat drug-resistant focal epilepsy. Here, we present the virtual …

[HTML][HTML] Hierarchical heterogeneity across human cortex shapes large-scale neural dynamics

M Demirtaş, JB Burt, M Helmer, JL Ji, BD Adkinson… - Neuron, 2019 - cell.com
The large-scale organization of dynamical neural activity across cortex emerges through
long-range interactions among local circuits. We hypothesized that large-scale dynamics are …

Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture

R Gao, RL Van den Brink, T Pfeffer, B Voytek - Elife, 2020 - elifesciences.org
Complex cognitive functions such as working memory and decision-making require
information maintenance over seconds to years, from transient sensory stimuli to long-term …

High‐frequency oscillations in the normal human brain

B Frauscher, N von Ellenrieder, R Zelmann… - Annals of …, 2018 - Wiley Online Library
Objective High‐frequency oscillations (HFOs) are a promising biomarker for the
epileptogenic zone. It has not been possible, however, to differentiate physiological from …

Normative intracranial EEG maps epileptogenic tissues in focal epilepsy

JM Bernabei, N Sinha, TC Arnold, E Conrad, I Ong… - Brain, 2022 - academic.oup.com
Planning surgery for patients with medically refractory epilepsy often requires recording
seizures using intracranial EEG. Quantitative measures derived from interictal intracranial …

Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study

K Wagstyl, K Whitaker, A Raznahan, J Seidlitz… - …, 2022 - Wiley Online Library
Objective Drug‐resistant focal epilepsy is often caused by focal cortical dysplasias (FCDs).
The distribution of these lesions across the cerebral cortex and the impact of lesion location …