Illuminating the future of precision cancer surgery with fluorescence imaging and artificial intelligence convergence

H Cheng, H Xu, B Peng, X Huang, Y Hu… - NPJ Precision …, 2024 - nature.com
Real-time and accurate guidance for tumor resection has long been anticipated by
surgeons. In the past decade, the flourishing material science has made impressive …

EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial

JG de Wit, J Vonk, FJ Voskuil, SAHJ de Visscher… - Nature …, 2023 - nature.com
Inadequate surgical margins occur frequently in oral squamous cell carcinoma surgery.
Fluorescence molecular imaging (FMI) has been explored for intraoperative margin …

Improving oral squamous cell carcinoma diagnosis and treatment with fluorescence molecular imaging

J Fu, A Alhaskawi, Y Dong, F **, J Chen, X Zou… - Photodiagnosis and …, 2023 - Elsevier
Timely identification and complete removal of oral squamous cell carcinoma (OSCC)
through surgery is crucial for effective treatment. However, current diagnostic methods that …

Quantifying the impact of signal-to-background ratios on surgical discrimination of fluorescent lesions

S Azargoshasb, I Boekestijn, M Roestenberg… - Molecular Imaging and …, 2023 - Springer
Purpose Surgical fluorescence guidance has gained popularity in various settings, eg,
minimally invasive robot-assisted laparoscopic surgery. In pursuit of novel receptor-targeted …

Immediate resection of positive margins improves local control in oral tongue cancer

L Zhang, RT Judd, S Zhao, C Rygalski, M Li, A Briody… - Oral Oncology, 2023 - Elsevier
Objectives This study investigates the impact of immediate resection of positive margins on
local control of oral tongue cancer. Materials and Methods We analyzed 273 consecutive …

Interim Phase II Results Using Panitumumab-IRDye800CW during Transoral Robotic Surgery in Patients with Oropharyngeal Cancer

LD Stone, BB Kasten, S Rao, ML Gonzalez… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has
continually increased during the past several decades. Using transoral robotic surgery …

[HTML][HTML] Comparison of narrow band and fluorescence molecular imaging to improve intraoperative tumour margin assessment in oral cancer surgery

JG de Wit, JE van Schaik, FJ Voskuil, J Vonk… - Oral Oncology, 2022 - Elsevier
Objective New techniques have emerged to aid in preventing inadequate margins in oral
squamous cell carcinoma (OSCC) surgery, but studies comparing different techniques are …

Comparison of quality of life and psychological distress in patients with tongue cancer undergoing a total/subtotal glossectomy or extended hemiglossectomy and free …

K Suzuki, N Nishio, H Kimura, T Tokura, S Kishi… - International Journal of …, 2023 - Elsevier
The aim of this study was to assess changes in the quality of life and psychological distress
of patients with tongue cancer undergoing total/subtotal glossectomy (TG) or extended …

Anatomy-specific classification model using label-free FLIm to aid intraoperative surgical guidance of head and neck cancer

MA Hassan, BW Weyers, J Bec… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Intraoperative identification of head and neck cancer tissue is essential to achieve complete
tumor resection and mitigate tumor recurrence. Mesoscopic fluorescence lifetime imaging …

Deep learning–enabled fluorescence imaging for surgical guidance: in silico training for oral cancer depth quantification

NJ Won, M Bartling, J La Macchia… - Journal of …, 2025 - spiedigitallibrary.org
Significance Oral cancer surgery requires accurate margin delineation to balance complete
resection with post-operative functionality. Current in vivo fluorescence imaging systems …