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Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
Overview of MMP-13 as a promising target for the treatment of osteoarthritis
Q Hu, M Ecker - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …
[HTML][HTML] Osteoarthritis pain
Joint pain is the hallmark symptom of osteoarthritis (OA) and the main reason for patients to
seek medical assistance. OA pain greatly contributes to functional limitations of joints and …
seek medical assistance. OA pain greatly contributes to functional limitations of joints and …
Exosomes: roles and therapeutic potential in osteoarthritis
Z Ni, S Zhou, S Li, L Kuang, H Chen, X Luo, J Ouyang… - Bone research, 2020 - nature.com
Exosomes participate in many physiological and pathological processes by regulating cell–
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …
cell communication, which are involved in numerous diseases, including osteoarthritis (OA) …
Biomechanics of chondrocytes and chondrons in healthy conditions and osteoarthritis: A review of the mechanical characterisations at the microscale
Biomechanical studies are expanding across a variety of fields, from biomedicine to
biomedical engineering. From the molecular to the system level, mechanical stimuli are …
biomedical engineering. From the molecular to the system level, mechanical stimuli are …
Erosive hand osteoarthritis: latest findings and outlook
Osteoarthritis (OA) most commonly affects knee joints, and the next most commonly affected
sites are the hands and hips. Three distinct hand OA phenotypes have been described …
sites are the hands and hips. Three distinct hand OA phenotypes have been described …
Human cartilage biomechanics: experimental and theoretical approaches towards the identification of mechanical properties in healthy and osteoarthritic conditions
Articular cartilage is a complex connective tissue with the fundamental functions of load
bearing, shock absorption and lubrication in joints. However, traumatic events, aging and …
bearing, shock absorption and lubrication in joints. However, traumatic events, aging and …
Infrapatellar fat pad-synovial membrane anatomo-fuctional unit: microscopic basis for Piezo1/2 mechanosensors involvement in osteoarthritis pain
The Infrapatellar Fat Pad (IFP) is a fibro-adipose tissue of the knee recently reconsidered as
part of a single anatomo-functional unit (AFU) together with the synovial membrane (SM) …
part of a single anatomo-functional unit (AFU) together with the synovial membrane (SM) …
Pathophysiology of musculoskeletal pain: a narrative review
F Puntillo, M Giglio, A Paladini… - Therapeutic …, 2021 - journals.sagepub.com
Musculoskeletal pain (excluding bone cancer pain) affects more than 30% of the global
population and imposes an enormous burden on patients, families, and caregivers related to …
population and imposes an enormous burden on patients, families, and caregivers related to …
The role of fibrosis in osteoarthritis progression
YA Rim, JH Ju - Life, 2020 - mdpi.com
Osteoarthritis (OA) is a chronic degenerative joint disease where the main characteristics
include cartilage degeneration and synovial membrane inflammation. These changes in the …
include cartilage degeneration and synovial membrane inflammation. These changes in the …