In the last few years, electron microscopy has experienced a new methodological paradigm
aimed to fix the bottlenecks and overcome the challenges of its analytical workflow. Machine …

The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …

Keratinocytes, the predominant cell type of the epidermis, migrate to reinstate the epithelial
barrier during wound healing. Mechanical cues are known to regulate keratinocyte re …

Cell and organelle shape are driven by diverse genetic and environmental factors and thus
accurate quantification of cellular morphology is essential to experimental cell biology …

Vascular smooth muscle cells (VSMCs) play a central role in the progression of
atherosclerosis, where they switch from a contractile to a synthetic phenotype. Because of …

In recent decades, 3D bioprinting has garnered significant research attention due to its
ability to manipulate biomaterials and cells to create complex structures precisely. However …

Metastasis is the leading cause of cancer-associated deaths, and the circulating tumor cell
(CTC) cluster plays a significant role as a precursor to metastasis. Thus, there is a great …

Uniquely among mammalian organs, skin is capable of marked size change in adults, yet
the mechanisms underlying this notable capacity are unclear. Here, we use a system of …

Spatially resolved transcriptomics (SRT) is a growing field that links gene expression to
anatomical context. SRT approaches that use next-generation sequencing (NGS) combine …

While the transcription factor NEUROD2 has recently been associated with epilepsy, its
precise role during nervous system development remains unclear. Using a multi-scale …