Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Emotions are powerful determinants of behaviour, thought and experience, and they may be
regulated in various ways. Neuroimaging studies have implicated several brain regions in …

Learning the value of stimuli and actions from others—social learning—adaptively
contributes to individual survival and plays a key role in cultural evolution. We review …

Importance Psychiatric diagnoses are currently distinguished based on sets of specific
symptoms. However, genetic and clinical analyses find similarities across a wide variety of …

Classical Pavlovian fear conditioning remains the most widely employed experimental
model of fear and anxiety, and continues to inform contemporary pathophysiological …

Emotions are valenced mental responses and associated physiological reactions that occur
spontaneously and automatically in response to internal or external stimuli, and can …

Objective: Although anxiety can be an adaptive response to unpredictable threats,
pathological anxiety disorders occur when symptoms adversely affect daily life. Whether or …

Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

The study of fear extinction represents an important example of translational neuroscience in
psychiatry and promises to improve the understanding and treatment of anxiety and fear …