The cerebrospinal fluid in multiple sclerosis
Investigation of cerebrospinal fluid (CSF) in the diagnostic work-up in suspected multiple
sclerosis (MS) patients has regained attention in the latest version of the diagnostic criteria …
sclerosis (MS) patients has regained attention in the latest version of the diagnostic criteria …
Proteomics in multiple sclerosis: the perspective of the clinician
D Sandi, Z Kokas, T Biernacki, K Bencsik… - International Journal of …, 2022 - mdpi.com
Multiple sclerosis (MS) is the inflammatory demyelinating and neurodegenerative disease of
the central nervous system (CNS) that affects approximately 2.8 million people worldwide. In …
the central nervous system (CNS) that affects approximately 2.8 million people worldwide. In …
Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis
G Hinsinger, N Galéotti, N Nabholz… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background: Despite sensitivity of MRI to diagnose multiple sclerosis (MS), prognostic
biomarkers are still needed for optimized treatment. Objective: The objective of this paper is …
biomarkers are still needed for optimized treatment. Objective: The objective of this paper is …
Role of Chitinase 3–like 1 as a biomarker in multiple sclerosis: a systematic review and meta-analysis
Background and Objectives Multiple sclerosis (MS) is an autoimmune disease confined in
the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers …
the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers …
Recent advances in quantitative neuroproteomics
The field of proteomics is undergoing rapid development in a number of different areas
including improvements in mass spectrometric platforms, peptide identification algorithms …
including improvements in mass spectrometric platforms, peptide identification algorithms …
Biomarkers of multiple sclerosis: current findings
VK Harris, JF Tuddenham, SA Sadiq - … and neuromuscular disease, 2017 - Taylor & Francis
Multiple sclerosis (MS) is an autoimmune disease affecting the brain and spinal cord that is
associated with chronic inflammation leading to demyelination and neurodegeneration. With …
associated with chronic inflammation leading to demyelination and neurodegeneration. With …
Biomarkers of therapeutic response in multiple sclerosis: current status
VK Harris, SA Sadiq - Molecular diagnosis & therapy, 2014 - Springer
Multiple sclerosis (MS) is an autoimmune disease of unknown cause, in which chronic
inflammation drives multifocal demyelination of axons in both white and gray matter in the …
inflammation drives multifocal demyelination of axons in both white and gray matter in the …
Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics
EL van der Ende, LH Meeter, C Stingl… - Annals of clinical …, 2019 - Wiley Online Library
Objective To identify novel CSF biomarkers in GRN‐associated frontotemporal dementia
(FTD) by proteomics using mass spectrometry (MS). Methods Unbiased MS was applied to …
(FTD) by proteomics using mass spectrometry (MS). Methods Unbiased MS was applied to …
Proteomics of multiple sclerosis: inherent issues in defining the pathoetiology and identifying (early) biomarkers
Multiple Sclerosis (MS) is a demyelinating disease of the human central nervous system
having an unconfirmed pathoetiology. Although animal models are used to mimic the …
having an unconfirmed pathoetiology. Although animal models are used to mimic the …
Molecular biomarkers in cerebrospinal fluid of multiple sclerosis patients
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system,
usually occurring in young adults and leading to disability. Despite the progress in …
usually occurring in young adults and leading to disability. Despite the progress in …