[HTML][HTML] Sex differences in Alzheimer's disease: insights from the multiomics landscape

L Guo, MB Zhong, L Zhang, B Zhang, D Cai - Biological psychiatry, 2022 - Elsevier
Alzheimer's disease (AD) has complex etiologies, and the impact of sex on AD varies over
the course of disease development. The literature provides some evidence of sex-specific …

Sex/gender differences in cognitive abilities

S Kheloui, S Jacmin-Park, O Larocque, P Kerr… - Neuroscience & …, 2023 - Elsevier
Sex/gender differences in cognitive sciences are riddled by conflicting perspectives. At the
center of debates are clinical, social, and political perspectives. Front and center …

Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review

B Zimmerman, B Rypma, G Gratton… - …, 2021 - Wiley Online Library
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …

Association between sex hormone levels and gut microbiota composition and diversity—a systematic review

M d'Afflitto, A Upadhyaya, A Green… - Journal of clinical …, 2022 - journals.lww.com
Results: A total of 10,468 records were screened with 13 studies included in this review. In
healthy women, higher estrogen levels were found to be associated with a higher …

A framework for develo** sex-specific engineered heart models

R Lock, H Al Asafen, S Fleischer, M Tamargo… - Nature Reviews …, 2022 - nature.com
The convergence of tissue engineering and patient-specific stem cell biology has enabled
the engineering of in vitro tissue models that allow the study of patient-tailored treatment …

[HTML][HTML] Steroid hormone sensitivity in reproductive mood disorders: on the role of the GABAA receptor complex and stress during hormonal transitions

S Schweizer-Schubert, JL Gordon… - Frontiers in …, 2021 - frontiersin.org
Women worldwide are two to three times more likely to suffer from depression in their
lifetime than are men. Female risk for depressive symptoms is particularly high during the …

[HTML][HTML] Modeling sex differences in humans using isogenic induced pluripotent stem cells

I Waldhorn, T Turetsky, D Steiner, Y Gil, H Benyamini… - Stem cell reports, 2022 - cell.com
Biological sex is a fundamental trait influencing development, reproduction, pathogenesis,
and medical treatment outcomes. Modeling sex differences is challenging because of the …

Female specific risk factors for the development of Alzheimer's disease neuropathology and cognitive impairment: Call for a precision medicine approach

C Udeh-Momoh, T Watermeyer - Ageing Research Reviews, 2021 - Elsevier
Alzheimer's disease (AD) includes a long asymptomatic stage, which precedes the formal
diagnosis of dementia. AD biomarker models provide a framework for precision medicine …

Sex-biased impact of endocrine disrupting chemicals on behavioral development and vulnerability to disease: Of mice and children

P Palanza, S Paterlini, MM Brambilla… - Neuroscience & …, 2021 - Elsevier
Sex is a fundamental biological characteristic that influences many aspects of an organism's
phenotype, including neurobiological functions and behavior as a result of species-specific …

Sex steroids and sex steroid‐binding globulin levels amongst middle‐aged and elderly men and women from general population

E Aribas, JE Roeters van Lennep… - European journal of …, 2022 - Wiley Online Library
Abstract Background and Aims Availability of age‐and sex‐specific reference values for sex
steroids and sex steroid‐binding globulin (SHBG) levels allows for appropriate interpretation …