Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

[HTML][HTML] Type 2 inflammation contributes to skin barrier dysfunction in atopic dermatitis

LA Beck, MJ Cork, M Amagai, A De Benedetto… - JID Innovations, 2022 - Elsevier
Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …

Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial

T Nakatsuji, TR Hata, Y Tong, JY Cheng, F Shafiq… - Nature medicine, 2021 - nature.com
Staphylococcus aureus colonizes patients with atopic dermatitis (AD) and exacerbates
disease by promoting inflammation. The present study investigated the safety and …

Skin microbiome of atopic dermatitis

LF Koh, RY Ong, JE Common - Allergology International, 2022 - jstage.jst.go.jp
abstract The skin microbiome is a key component of pathogenesis in atopic dermatitis (AD).
The skin of AD patients is characterized by microbial dysbiosis, with a reduction of microbial …

[HTML][HTML] The infectious complications of atopic dermatitis

V Wang, J Boguniewicz, M Boguniewicz… - Annals of Allergy, Asthma …, 2021 - Elsevier
Objective Atopic dermatitis (AD) is a chronic inflammatory skin disease that is complicated
by an increased risk for skin and systemic infections. Preventive therapy for AD is based on …

The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group

H Alexander, AS Paller… - British Journal of …, 2020 - academic.oup.com
Patients with atopic dermatitis (AD) have an increased risk of bacterial skin infections, which
cause significant morbidity and, if untreated, may become systemic. Staphylococcus aureus …

[HTML][HTML] Skin microbiome in atopic dermatitis

SM Edslev, T Agner, PS Andersen - Acta dermato-venereologica, 2020 - ncbi.nlm.nih.gov
Atopic dermatitis is a common inflammatory skin disease with a complex pathogenesis that
includes imbalanced immune system signalling, impaired skin barrier and enhanced …

Atopic dermatitis: pathomechanisms and lessons learned from novel systemic therapeutic options

T Bieber, AS Paller, K Kabashima… - Journal of the …, 2022 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, heterogenous, inflammatory skin disorder associated
with a high skin‐related health burden, typically starting in childhood and often persisting …

The translational revolution in atopic dermatitis: the paradigm shift from pathogenesis to treatment

P Facheris, J Jeffery, E Del Duca… - Cellular & Molecular …, 2023 - nature.com
Atopic dermatitis (AD) is the most common inflammatory skin disease, and it is considered a
complex and heterogeneous condition. Different phenotypes of AD, defined according to the …

The skin microbiome in the first year of life and its association with atopic dermatitis

A Rapin, EM Rehbinder, M Macowan, C Pattaroni… - Allergy, 2023 - Wiley Online Library
Background Early‐life microbial colonization of the skin may modulate the immune system
and impact the development of atopic dermatitis (AD) and allergic diseases later in life. To …