Oxidative stress and regulated cell death in Parkinson's disease

PA Dionísio, JD Amaral, CMP Rodrigues - Ageing research reviews, 2021 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Motor deficits usually associated with PD correlate with dopaminergic axonal …

Biomarkers for parkinsonian disorders in CNS-originating EVs: promise and challenges

S Dutta, S Hornung, HB Taha, G Bitan - Acta Neuropathologica, 2023 - Springer
Extracellular vesicles (EVs), including exosomes, microvesicles, and oncosomes, are nano-
sized particles enclosed by a lipid bilayer. EVs are released by virtually all eukaryotic cells …

Parkinson's disease: biomarkers, treatment, and risk factors

FN Emamzadeh, A Surguchov - Frontiers in neuroscience, 2018 - frontiersin.org
Parkinson's disease (PD) is a progressive neurodegenerative disorder caused mainly by
lack of dopamine in the brain. Dopamine is a neurotransmitter involved in movement …

Emergence of extracellular vesicles as “liquid biopsy” for neurological disorders: boom or bust

A Kumar, MA Nader, G Deep - Pharmacological reviews, 2024 - Elsevier
Extracellular vesicles (EVs) have emerged as an attractive liquid biopsy approach in the
diagnosis and prognosis of multiple diseases and disorders. The feasibility of enriching …

Research progress on the role of extracellular vesicles in neurodegenerative diseases

Z Li, X Wang, X Wang, X Yi, YK Wong, J Wu… - Translational …, 2023 - Springer
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease, affect millions of people worldwide …

The role of noncoding RNAs in Parkinson's disease: biomarkers and associations with pathogenic pathways

MC Kuo, SCH Liu, YF Hsu, RM Wu - Journal of biomedical science, 2021 - Springer
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a
growing area in cell biology. Increasing evidence has revealed canonical and noncanonical …

Exosome determinants of physiological aging and age-related neurodegenerative diseases

M D'Anca, C Fenoglio, M Serpente, B Arosio… - Frontiers in aging …, 2019 - frontiersin.org
Aging is consistently reported as the most important independent risk factor for
neurodegenerative diseases. As life expectancy has significantly increased during the last …

MicroRNA dysregulation in Parkinson's disease: a narrative review

YH Nies, NH Mohamad Najib, WL Lim… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a severely debilitating neurodegenerative disease, affecting the
motor system, leading to resting tremor, cogwheel rigidity, bradykinesia, walking and gait …

Extracellular vesicles for the diagnosis of Parkinson's disease: systematic review and meta‐analysis

M Xylaki, A Chopra, S Weber, M Bartl… - Movement …, 2023 - Wiley Online Library
Parkinson's disease (PD) biomarkers are needed by both clinicians and researchers (for
diagnosis, identifying study populations, and monitoring therapeutic response). Imaging …

[HTML][HTML] Update on CSF biomarkers in Parkinson's disease

EH Kwon, S Tennagels, R Gold, K Gerwert, L Beyer… - Biomolecules, 2022 - mdpi.com
Progress in develo** disease-modifying therapies in Parkinson's disease (PD) can only
be achieved through reliable objective markers that help to identify subjects at risk. This …