Can insects feel pain? A review of the neural and behavioural evidence

M Gibbons, A Crump, M Barrett, S Sarlak, J Birch… - Advances in Insect …, 2022 - Elsevier
The entomology literature has historically suggested insects cannot feel pain, leading to
their exclusion from ethical debates and animal welfare legislation. However, there may be …

Gustation in insects: taste qualities and types of evidence used to show taste function of specific body parts

BH King, PB Gunathunga - Journal of Insect Science, 2023 - academic.oup.com
The insect equivalent of taste buds are gustatory sensilla, which have been found on
mouthparts, pharynxes, antennae, legs, wings, and ovipositors. Most gustatory sensilla are …

Drosophila menthol sensitivity and the Precambrian origins of transient receptor potential-dependent chemosensation

NJ Himmel, JM Letcher, A Sakurai… - … of the Royal …, 2019 - royalsocietypublishing.org
Transient receptor potential (TRP) cation channels are highly conserved, polymodal sensors
which respond to a wide variety of stimuli. Perhaps most notably, TRP channels serve critical …

Thymol activates TRPM8-mediated Ca2+ influx for its antipruritic effects and alleviates inflammatory response in Imiquimod-induced mice

W Wang, H Wang, Z Zhao, X Huang, H **ong… - Toxicology and Applied …, 2020 - Elsevier
Psoriasis is a highly prevalent chronic dermatitis, characterized by widespread skin
inflammation and spontaneous itch. Given the adverse reactions and drug dependence of …

Involvement of the gut microbiota in the metabolic phenotypes of two sympatric gerbils

J Wen, W Li, T Bo, B Ding, X Zhang, D Wang - … Biochemistry and Physiology …, 2024 - Elsevier
Temporal niche partitioning is a crucial strategy for sympatric species to avoid predation and
competition for habitat space and food resources. This study investigated the effect of the gut …

Capsaicin preferentially inhibits slow-inactivation sodium currents in insects

M Kamezaki, H Nishiwaki - Toxicon, 2025 - Elsevier
Capsaicin, a pungent ingredient found in chili peppers, exhibits various pharmacological
activities including inhibiting voltage-gated sodium channels (VGSCs) in mammals …

[HTML][HTML] An Overview of Ion Channels Therapeutics in the Treatment of Pain

YI Asiri, MZ Hassan - Arabian Journal of Chemistry, 2023 - Elsevier
Significance of the study: The clinical management of severe and chronic pain relies heavily
on opioids that cause serious side-effects. There therefore exists an urgent need to develop …

Molecular bases of sensory processes in kissing bugs, vectors of Chagas disease

JM Latorre-Estivalis, MG Lorenzo - Current opinion in insect science, 2019 - Elsevier
Highlights•Kissing bugs are hematophagous insects that act as vectors of human
disease.•The detection of multimodal sensory inputs related to host, shelter, and sexual …

Octopamine is involved in TRP-induced thermopreference responses in American cockroach

J Maliszewska, M Jankowska, J Rogalska - Journal of Insect Physiology, 2024 - Elsevier
Insects' thermoregulatory processes depend on thermosensation and further processing of
thermal information in the nervous system. It is commonly known that thermosensation …

Noxious stimulation induces self-protective behavior in bumblebees

L Chittka, M Gibbons, A Kowalewka, E Pasquini… - iScience, 2024 - qmro.qmul.ac.uk
It has been widely stated that insects do not show self-protective behavior towards noxiously-
stimulated body parts, but this claim has never been empirically tested. Here, we tested …