Graphic, Quantitation, Visualization, Standardization, Digitization, and Intelligence of Electrolyte and Electrolyte‐Electrode Interface

T Cai, Y Wang, F Zhao, Z Ma, P Kumar… - Advanced Energy …, 2024‏ - Wiley Online Library
Electrolytes have recently regained significant attention in rechargeable batteries due to the
discovery that the electrolyte microstructures play a determinant role in battery performance …

Inflammatory and microbiota-related regulation of the intestinal epithelial barrier

G Barbara, MR Barbaro, D Fuschi, M Palombo… - Frontiers in …, 2021‏ - frontiersin.org
The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

A guide to plasma membrane solute carrier proteins

MD Pizzagalli, A Bensimon… - The FEBS …, 2021‏ - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

Nanotechnology for enhanced nose-to-brain drug delivery in treating neurological diseases

Q Huang, Y Chen, W Zhang, X **a, H Li, M Qin… - Journal of controlled …, 2024‏ - Elsevier
Despite the increasing global incidence of brain disorders, achieving sufficient delivery
towards the central nervous system (CNS) remains a formidable challenge in terms of …

The expanding role of prodrugs in contemporary drug design and development

J Rautio, NA Meanwell, L Di… - Nature reviews drug …, 2018‏ - nature.com
Prodrugs are molecules with little or no pharmacological activity that are converted to the
active parent drug in vivo by enzymatic or chemical reactions or by a combination of the two …

Layered double hydroxides: A brief review from fundamentals to application as evolving biomaterials

G Mishra, B Dash, S Pandey - Applied Clay Science, 2018‏ - Elsevier
Layered double hydroxides (LDH) which are one type of layered materials and are also
known as anionic clays, are promising layered materials due to some of their interesting …

The time and place for nature in drug discovery

RJ Young, SL Flitsch, M Grigalunas, PD Leeson… - Jacs Au, 2022‏ - ACS Publications
The case for a renewed focus on Nature in drug discovery is reviewed; not in terms of
natural product screening, but how and why biomimetic molecules, especially those …

A boiled‐egg to predict gastrointestinal absorption and brain penetration of small molecules

A Daina, V Zoete - ChemMedChem, 2016‏ - Wiley Online Library
Apart from efficacy and toxicity, many drug development failures are imputable to poor
pharmacokinetics and bioavailability. Gastrointestinal absorption and brain access are two …

Bioavailability of bioactive peptides derived from food proteins across the intestinal epithelial membrane: A review

Q Xu, H Hong, J Wu, X Yan - Trends in Food Science & Technology, 2019‏ - Elsevier
Abstract Background Bioactive peptides (BAPs) play a crucial physiological role in human
health. To exert their biological effects after oral administration, BAPs have to be transported …

[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery

EM Del Amo, AK Rimpelä, E Heikkinen, OK Kari… - Progress in retinal and …, 2017‏ - Elsevier
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …