Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Functional DNA–polymer conjugates

CJ Whitfield, M Zhang, P Winterwerber, Y Wu… - Chemical …, 2021 - ACS Publications
DNA nanotechnology has seen large developments over the last 30 years through the
combination of solid phase synthesis and the discovery of DNA nanostructures. Solid phase …

Photophysics of preassociated pyrenes in aqueous polymer solutions and in other organized media

FM Winnik - Chemical reviews, 1993 - ACS Publications
In the course of a study of anthryl-labeled polyionenes in water Suzuki and Tazuke noticed
rather unusual patterns in the absorption and emission spectra of anthracene. 1 The …

Nucleosidic and non-nucleosidic folate conjugates

AP Guzaev, PD Cook, M Manoharan, B Bhat - US Patent 6,335,434, 2002 - Google Patents
4,828,979 A 5/1989 Klevan et a1_ _ __ 435/6 5,416,016 A 5/1995 Low et al..................
435/240.1 4,835,263 A 5/1989 Nguyen et a1_ 536/27 5,416,203 A 5/1995 …

Bubble dynamics in double-stranded DNA

G Altan-Bonnet, A Libchaber, O Krichevsky - Physical review letters, 2003 - APS
We report the first measurement of the dynamics of bubble formation in double-stranded
DNA. Fluctuations of fluorescence of a synthetic DNA construct, internally tagged with a …

Oligonucleotide-folate conjugates

PD Cook, M Manoharan, B Bhat - US Patent 6,528,631, 2003 - Google Patents
Oligonucleotide-folate conjugates are described wherein folates are conjugated to one or
more sites on an oligonucleotide including the 2′-, 3′-, 5′-, nucleobase and …

The functionalization of oligonucleotides via phosphoramidite derivatives

SL Beaucage, RP Iyer - Tetrahedron, 1993 - Elsevier
The rapid growth of biotechnology has triggered an increasing demand for modified
oligonucleotides dedicated mostly to diagnostic and therapeutic applications. The plethoric …

Derivatized oligonucleotides having improved uptake and other properties

M Manoharan, PD Cook, CF Bennett - US Patent 6,153,737, 2000 - Google Patents
Linked nucleosides having at least one functionaliZed nucleoside that bears a substituent
such as a steroid molecule, a reporter molecule, a non-aromatic lipophilic molecule, a …

Intercalating nucleic acids containing insertions of 1‐ O ‐(1‐pyrenylmethyl)glycerol: stabilisation of dsDNA and discrimination of DNA over RNA

UB Christensen, EB Pedersen - Nucleic Acids Research, 2002 - academic.oup.com
We have studied hybridisation affinities and fluorescence behaviour of intercalator‐modified
oligonucleotides. The phosphoramidite of (S)‐1‐O‐(4, 4′‐dimethoxytriphenylmethyl)‐3‐O …

Alkynylpyrenes as improved pyrene‐based biomolecular probes with the advantages of high fluorescence quantum yields and long absorption/emission wavelengths

H Maeda, T Maeda, K Mizuno… - … A European Journal, 2006 - Wiley Online Library
The photochemical properties of various alkynylpyrene derivatives have been investigated
in detail with a view to develo** a new class of pyrene‐based biomolecular probes. The …