How do red blood cells die?

P Thiagarajan, CJ Parker, JT Prchal - Frontiers in physiology, 2021 - frontiersin.org
Normal human red blood cells have an average life span of about 120 days in the circulation
after which they are engulfed by macrophages. This is an extremely efficient process as …

Sialic acids as receptors for pathogens

P Burzyńska, ŁF Sobala, K Mikołajczyk, M Jodłowska… - Biomolecules, 2021 - mdpi.com
Carbohydrates have long been known to mediate intracellular interactions, whether within
one organism or between different organisms. Sialic acids (Sias) are carbohydrates that …

Erythrocyte glycophorins as receptors for Plasmodium merozoites

E Jaskiewicz, M Jodłowska, R Kaczmarek, A Zerka - Parasites & vectors, 2019 - Springer
Glycophorins are heavily glycosylated sialoglycoproteins of human and animal erythrocytes.
In humans, there are four glycophorins: A, B, C and D. Glycophorins play an important role in …

Rosetting revisited: a critical look at the evidence for host erythrocyte receptors in Plasmodium falciparum rosetting

F McQuaid, JA Rowe - Parasitology, 2020 - cambridge.org
Malaria remains a major cause of mortality in African children, with no adjunctive treatments
currently available to ameliorate the severe clinical forms of the disease. Rosetting, the …

[HTML][HTML] Three non-classical mechanisms for anemic disease of the fetus and newborn, based on maternal anti-Kell, anti-Ge3, anti-M, and anti-Jra cases

H Ohto, GA Denomme, S Ito, A Ishida, KE Nollet… - … and Apheresis Science, 2020 - Elsevier
Maternal alloantibody-mediated hemolytic disease of the fetus and newborn (HDFN) ranges
from no or mild symptoms to severe hydrops and intrauterine fetal demise. Hemolytic anti-D …

Genetic variation of glycophorins and infectious disease

EJ Hollox, S Louzada - Immunogenetics, 2023 - Springer
Glycophorins are transmembrane proteins of red blood cells (RBCs), heavily glycosylated
on their external-facing surface. In humans, there are four glycophorin proteins, glycophorins …

The monocyte monolayer assay: past, present and future

TN Tong, S Cen, DR Branch - Transfusion Medicine Reviews, 2019 - Elsevier
Serologic testing using the indirect antiglobulin test (IAT) is known to be insufficient to
determine the clinical significance or insignificance of a given antibody to red blood cells …

The Gardos effect drives erythrocyte senescence and leads to Lu/BCAM and CD44 adhesion molecule activation

TRL Klei, JJ Dalimot, BM Beuger, M Veldthuis… - Blood …, 2020 - ashpublications.org
Senescence of erythrocytes is characterized by a series of changes that precede their
removal from the circulation, including loss of red cell hydration, membrane shedding, loss …

[HTML][HTML] Kell Blood Group System

A Maheshwari, M Zubair, A Maheshwari - StatPearls [Internet], 2024 - ncbi.nlm.nih.gov
The Kell blood group system is vast, with 38 blood group antigens.[1] The Kell system is
notorious for its immunogenicity, which is third after ABO and Rhesus D.[2] This system is …

[HTML][HTML] Common differentially expressed genes and pathways correlating both coronary artery disease and atrial fibrillation

Y Zheng, JQ He - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Coronary artery disease (CAD) and atrial fibrillation (AF) share common risk factors, such as
hypertension and diabetes. The patients with CAD often suffer concomitantly AF, but how …