MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics
A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …
remaining incurable with a median survival time of only 15 months. In an effort to identify …
Glioblastoma therapy in the age of molecular medicine
Glioblastoma (GBM) is the most common and fatal primary malignant brain tumor. Despite
advances in the understanding of the biology of gliomas, little has changed in the treatment …
advances in the understanding of the biology of gliomas, little has changed in the treatment …
Brain targeted gold liposomes improve RNAi delivery for glioblastoma
N Grafals-Ruiz, CI Rios-Vicil… - International Journal …, 2020 - Taylor & Francis
Introduction Glioblastoma (GBM) is the most common and lethal of the central nervous
system (CNS) malignancies. The initiation, progression, and infiltration ability of GBMs are …
system (CNS) malignancies. The initiation, progression, and infiltration ability of GBMs are …
miR-448 targets IDO1 and regulates CD8+ T cell response in human colon cancer
Q Lou, R Liu, X Yang, W Li, L Huang, L Wei… - … for immunotherapy of …, 2019 - Springer
Abstract Background Indoleamine 2, 3-dioxygenase 1 (IDO1) is a critical regulator of T cell
function, contributing to immune tolerance. Upregulation of IDO1 has been found in many …
function, contributing to immune tolerance. Upregulation of IDO1 has been found in many …
MicroRNAs as biomarkers for human glioblastoma: progress and potential
S Huang, N Ali, L Zhong, J Shi - Acta Pharmacologica Sinica, 2018 - nature.com
Glioblastoma multiforme (GBM) is the most common malignant glioma. Despite innovative
research efforts in tumor therapy, the outcome for most diagnosed patients remains poor; …
research efforts in tumor therapy, the outcome for most diagnosed patients remains poor; …
Glioblastoma–Astrocyte Connexin 43 Gap Junctions Promote Tumor Invasion
Glioblastoma multiforme (GBM), classified as World Health Organization grade IV
astrocytoma, is the deadliest adult cancer of the central nervous system. An important …
astrocytoma, is the deadliest adult cancer of the central nervous system. An important …
RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials
EL Lozada-Delgado, N Grafals-Ruiz, PE Vivas-Mejía - Life sciences, 2017 - Elsevier
Glioblastoma multiforme (GBM) is the most common and deadliest type of primary brain
tumor with a prognosis of 14 months after diagnosis. Current treatment for GBM patients …
tumor with a prognosis of 14 months after diagnosis. Current treatment for GBM patients …
Deep learning/artificial intelligence and blood-based DNA epigenomic prediction of cerebral palsy
The etiology of cerebral palsy (CP) is complex and remains inadequately understood. Early
detection of CP is an important clinical objective as this improves long term outcomes. We …
detection of CP is an important clinical objective as this improves long term outcomes. We …
MicroRNA as potential biomarkers in Glioblastoma
Glioblastoma is the most aggressive and lethal tumour of the central nervous system and as
such the identification of reliable prognostic and predictive biomarkers for patient survival …
such the identification of reliable prognostic and predictive biomarkers for patient survival …
Use of microRNAs as Diagnostic, Prognostic, and Therapeutic Tools for Glioblastoma
Glioblastoma (GB) is the most aggressive and common type of cancer within the central
nervous system (CNS). Despite the vast knowledge of its physiopathology and histology, its …
nervous system (CNS). Despite the vast knowledge of its physiopathology and histology, its …