Mechanical signalling affects multiple biological processes during development and in adult
organisms, including cell fate transitions, cell migration, morphogenesis and immune …

Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

Clathrin-mediated endocytosis (CME) involves nanoscale bending and inward budding of
the plasma membrane, by which cells regulate both the distribution of membrane proteins …

Microbial biochemicals have been indicated as the primary stimulators of innate immunity,
the first line of the body's defence against infections. However, the influence of topological …

Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …

Actin filament assembly typically occurs in association with cellular membranes. A large
number of proteins sit at the interface between actin networks and membranes, playing …

Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin
filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell …

The enormous cellular diversity in the mammalian brain, which is highly prototypical and
organized in a hierarchical manner, is dictated by cell-type–specific gene-regulatory …

Glutaminase (GLS) isoenzymes GLS1 and GLS2 are key enzymes for glutamine
metabolism. Interestingly, GLS1 and GLS2 display contrasting functions in tumorigenesis …