Driven by applications in chemical sensing, biological imaging and material
characterisation, Raman spectroscopies are attracting growing interest from a variety of …

BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …

Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Second-harmonic generation (SHG) microscopy has emerged as a powerful modality for
imaging fibrillar collagen in a diverse range of tissues. Because of its underlying physical …

An imaging platform based on broadband coherent anti-Stokes Raman scattering has been
developed that provides an advantageous combination of speed, sensitivity and spectral …

Plasmonic nanostructures are of particular interest as substrates for the spectroscopic
detection and identification of individual molecules. Single-molecule sensitivity Raman …

Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging
technique that is capable of real-time, nonperturbative examination of living cells and …

The quest for ultrahigh detection sensitivity with spectroscopic contrasts other than
fluorescence has led to various novel approaches to optical microscopy of biological …

Coherent anti-Stokes Raman scattering (CARS) microscopy permits vibrational imaging with
high-sensitivity, high speed, and three-dimensional spatial resolution. We review recent …

Imaging living organisms with molecular selectivity typically requires the introduction of
specific labels. Many applications in biology and medicine, however, would significantly …