Directional deep brain stimulation: an intraoperative double-blind pilot study

C Pollo, A Kaelin-Lang, MF Oertel, L Stieglitz, E Taub… - Brain, 2014 - academic.oup.com
Deep brain stimulation of different targets has been shown to drastically improve symptoms
of a variety of neurological conditions. However, the occurrence of disabling side effects may …

Tractography patterns of subthalamic nucleus deep brain stimulation

N Vanegas-Arroyave, PM Lauro, L Huang, M Hallett… - Brain, 2016 - academic.oup.com
Deep brain stimulation therapy is an effective symptomatic treatment for Parkinson's
disease, yet the precise mechanisms responsible for its therapeutic effects remain unclear …

The active electrode in the living brain: the response of the brain parenchyma to chronically implanted deep brain stimulation electrodes

J Evers, M Lowery - Operative Neurosurgery, 2021 - journals.lww.com
BACKGROUND Deep brain stimulation is an established symptomatic surgical therapy for
Parkinson disease, essential tremor, and a number of other movement and neuropsychiatric …

Long-term surface electrode impedance recordings associated with gliosis for a closed-loop neurostimulation device

KA Sillay, S Ondoma, B Wingeier, D Schomberg… - Annals of …, 2019 - karger.com
Background: Closed-loop neurostimulation is a novel alternative therapy for medically
intractable focal epilepsy for patients who are not candidates for surgical resection of a …

Refining the deep brain stimulation target within the limbic globus pallidus internus for Tourette syndrome

L Akbarian-Tefaghi, H Akram, J Johansson… - Stereotactic and …, 2017 - karger.com
Background: Deep brain stimulation (DBS) in patients with severe, refractory Tourette
syndrome (TS) has demonstrated promising but variable results thus far. The thalamus and …

Subthalamic nucleus dynamics track microlesion effect in Parkinson's disease

C Peng, Z Wang, Y Sun, Y Mo, K Hu, Q Li… - Frontiers in Cell and …, 2024 - frontiersin.org
Parkinson's Disease (PD) is characterized by the temporary alleviation of motor symptoms
following electrode implantation (or nucleus destruction), known as the microlesion effect …

DBS proc: an open source process for DBS electrode localization and tractographic analysis

PM Lauro, N Vanegas‐Arroyave, L Huang, PA Taylor… - 2016 - Wiley Online Library
Deep brain stimulation (DBS) is an effective surgical treatment for movement disorders.
Although stimulation sites for movement disorders such as Parkinson's disease are …

Effect of anisotropic brain conductivity on patient-specific volume of tissue activation in deep brain stimulation for Parkinson disease

X Liu, KL Chou, PG Patil… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Objective: Deep brain stimulation (DBS) modeling can improve surgical targeting by
quantifying the spatial extent of stimulation relative to subcortical structures of interest. A …

Patient-specific simulations of deep brain stimulation electric field with aid of in-house software ELMA

JD Johansson, F Alonso… - 2019 41st annual …, 2019 - ieeexplore.ieee.org
Deep brain stimulation (DBS) is an established technique for reduction of symptoms in
movement disorders. Finite element method (FEM) simulations of the electric field …

Constant current versus constant voltage subthalamic nucleus deep brain stimulation in Parkinson's disease

F Ramirez de Noriega, R Eitan, O Marmor… - Stereotactic and …, 2015 - karger.com
Background: Subthalamic nucleus (STN) deep brain stimulation (DBS) is an established
therapy for advanced Parkinson's disease (PD). Motor efficacy and safety have been …