[Retracted] Global Increase in Breast Cancer Incidence: Risk Factors and Preventive Measures

D Kashyap, D Pal, R Sharma, VK Garg… - BioMed research …, 2022 - Wiley Online Library
Breast cancer is a global cause for concern owing to its high incidence around the world.
The alarming increase in breast cancer cases emphasizes the management of disease at …

Machine learning approaches to drug response prediction: challenges and recent progress

G Adam, L Rampášek, Z Safikhani, P Smirnov… - NPJ precision …, 2020 - nature.com
Cancer is a leading cause of death worldwide. Identifying the best treatment using
computational models to personalize drug response prediction holds great promise to …

DeLTA: Automated cell segmentation, tracking, and lineage reconstruction using deep learning

JB Lugagne, H Lin, MJ Dunlop - PLoS computational biology, 2020 - journals.plos.org
Microscopy image analysis is a major bottleneck in quantification of single-cell microscopy
data, typically requiring human oversight and curation, which limit both accuracy and …

Methods for copy number aberration detection from single-cell DNA-sequencing data

XF Mallory, M Edrisi, N Navin, L Nakhleh - Genome biology, 2020 - Springer
Copy number aberrations (CNAs), which are pathogenic copy number variations (CNVs),
play an important role in the initiation and progression of cancer. Single-cell DNA …

Deciphering tumour heterogeneity: from tissue to liquid biopsy

P Gilson, JL Merlin, A Harlé - Cancers, 2022 - mdpi.com
Simple Summary Most malignant tumours are highly heterogeneous at molecular and
phenotypic levels. Tumour variability poses challenges for the management of patients, as it …

Circulating tumour cells in the-omics era: how far are we from achieving the 'singularity'?

TH Visal, P den Hollander, M Cristofanilli… - British journal of …, 2022 - nature.com
Over the past decade, cancer diagnosis has expanded to include liquid biopsies in addition
to tissue biopsies. Liquid biopsies can result in earlier and more accurate diagnosis and …

Single cell multi-omics technology: methodology and application

Y Hu, Q An, K Sheu, B Trejo, S Fan… - Frontiers in cell and …, 2018 - frontiersin.org
In the era of precision medicine, multi-omics approaches enable the integration of data from
diverse omics platforms, providing multi-faceted insight into the interrelation of these omics …

Evaluation of cell type annotation R packages on single-cell RNA-seq data

Q Huang, Y Liu, Y Du, LX Garmire - Genomics, Proteomics and …, 2021 - academic.oup.com
Annotating cell types is a critical step in single-cell RNA sequencing (scRNA-seq) data
analysis. Some supervised or semi-supervised classification methods have recently …

The underlying tumor genomics of predominant histologic subtypes in lung adenocarcinoma

R Caso, F Sanchez-Vega, KS Tan… - Journal of Thoracic …, 2020 - Elsevier
Introduction The purpose of the study is to genomically characterize the biology and related
therapeutic opportunities of prognostically important predominant histologic subtypes in lung …

Single cell transcriptome research in human placenta

H Li, Q Huang, Y Liu, LX Garmire - Reproduction, 2020 - rep.bioscientifica.com
Human placenta is a complex and heterogeneous organ interfacing between the mother
and the fetus that supports fetal development. Alterations to placental structural components …