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Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses
Pre-existing cross-reactive immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …
Circular RNA vaccine in disease prevention and treatment
D Niu, Y Wu, J Lian - Signal transduction and targeted therapy, 2023 - nature.com
CircRNAs are a class of single-stranded RNAs with covalently linked head-to-tail topology.
In the decades since its initial discovery, their biogenesis, regulation, and function have …
In the decades since its initial discovery, their biogenesis, regulation, and function have …
B-cell and antibody responses to SARS-CoV-2: infection, vaccination, and hybrid immunity
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …
prompted scientific, medical, and biotech communities to investigate infection-and vaccine …
The role of vaccines in the COVID-19 pandemic: what have we learned?
F Krammer - Seminars in Immunopathology, 2024 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and
caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed …
caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed …
Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane
The entry of SARS-CoV-2 into host cells depends on the refolding of the virus-encoded
spike protein from a prefusion conformation, which is metastable after cleavage, to a lower …
spike protein from a prefusion conformation, which is metastable after cleavage, to a lower …
Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages have
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge
Abstract Ever-evolving SARS-CoV-2 variants of concern (VOCs) have diminished the
effectiveness of therapeutic antibodies and vaccines. Develo** a coronavirus vaccine that …
effectiveness of therapeutic antibodies and vaccines. Develo** a coronavirus vaccine that …
Viral membrane fusion: a dance between proteins and lipids
There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …
members of high concern for global human health. All enveloped viruses have a dedicated …