Recurrent mass bleaching events are pushing coral reefs worldwide to the brink of
ecological collapse. While the symptoms and consequences of this breakdown of the coral …

Ichthyosporea is an underexplored group of unicellular eukaryotes closely related to
animals. Thanks to their phylogenetic position, genomic content, and development through a …

Animals and fungi have radically distinct morphologies, yet both evolved within the same
eukaryotic supergroup: Opisthokonta,. Here we reconstructed the trajectory of genetic …

Highlights•Many of life's adaptive accessory functions are encoded in metabolic gene
clusters.•Cluster evolution is intertwined with the processes generating accessory …

Oceanic deoxygenation is increasingly affecting marine ecosystems; many taxa will be
severely challenged, yet certain nominally aerobic foraminifera (rhizarian protists) thrive in …

Coevolution at the gene level, as reflected by correlated events of gene loss or gain, can be
revealed by phylogenetic profile analysis. The optimal method and metric for comparing …

Gene clusters are genomic loci that contain multiple genes that are functionally and
genetically linked. Gene clusters collectively encode diverse functions, including small …

Gene clusters comprise genomically co-localized and potentially co-regulated genes that
tend to be conserved across species. In eukaryotes, multiple examples of metabolic gene …

A variety of secondary metabolites contributing to plant growth are synthesized by bacterial
nonribosomal peptide synthases (NRPSs). Among them, the NRPS biosynthesis of surfactin …

Cobalamin is a cofactor present in essential metabolic pathways in animals and one of the
water-soluble vitamins. It is a complex compound synthesized solely by prokaryotes …