Recombinant vaccines in 2022: a perspective from the cell factory

MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …

[HTML][HTML] Fish innate immune response to viral infection—An overview of five major antiviral genes

MM Ortega-Villaizan, V Chico, L Perez - Viruses, 2022 - mdpi.com
Fish viral diseases represent a constant threat to aquaculture production. Thus, a better
understanding of the cellular mechanisms involved in establishing an antiviral state …

Polystyrene nanoplastics accumulate in ZFL cell lysosomes and in zebrafish larvae after acute exposure, inducing a synergistic immune response in vitro without …

I Brandts, M Garcia-Ordoñez, L Tort, M Teles… - Environmental Science …, 2020 - pubs.rsc.org
The presence of small-sized plastic particles in marine and freshwater environments is a
global problem but their long-term impact on ecosystems and human health is still far from …

Self-assembling ferritin nanoplatform for the development of infectious hematopoietic necrosis virus vaccine

S Ahmadivand, Z Krpetic, MM Martínez… - Frontiers in …, 2024 - frontiersin.org
Self-assembling protein nanoparticles are used as a novel vaccine design platform to
improve the stability and immunogenicity of safe subunit vaccines, while providing broader …

[HTML][HTML] Zebrafish models for the safety and therapeutic testing of nanoparticles with a focus on macrophages

A Pensado-López, J Fernández-Rey, P Reimunde… - Nanomaterials, 2021 - mdpi.com
New nanoparticles and biomaterials are increasingly being used in biomedical research for
drug delivery, diagnostic applications, or vaccines, and they are also present in numerous …

Fish red blood cells modulate immune genes in response to bacterial inclusion bodies made of TNFα and a G-VHSV fragment

S Puente-Marin, R Thwaite, L Mercado, J Coll… - Frontiers in …, 2019 - frontiersin.org
Fish Red-Blood Cells (RBCs) are nucleated cells that can modulate the expression of
different sets of genes in response to stimuli, playing an active role in the homeostasis of the …

Immune functions of erythrocytes in osteichthyes

M Stosik, B Tokarz-Deptuła, J Deptuła… - Frontiers in …, 2020 - frontiersin.org
Red blood cells (RBCs)—erythrocytes—of Osteichthyes are primarily known for their
involvement in the process of gas exchange and respiration. Currently, physiological …

[HTML][HTML] Nanoparticle-enhanced fish feed: Benefits and challenges

E Dube - Fishes, 2024 - mdpi.com
Aquaculture production is continuously increasing, consequently increasing the demand for
feed. Unfortunately, the reliance on fish meal and fish oil also raises sustainability issues …

The poly-histidine tag H6 mediates structural and functional properties of disintegrating, protein-releasing inclusion bodies

JM Sánchez, JV Carratalá, N Serna, U Unzueta… - Pharmaceutics, 2022 - mdpi.com
The coordination between histidine-rich peptides and divalent cations supports the
formation of nano-and micro-scale protein biomaterials, including toxic and non-toxic …

Nanostructured recombinant protein particles raise specific antibodies against the nodavirus NNV coat protein in sole

R Thwaite, C Berbel, M Aparicio, D Torrealba… - Fish & Shellfish …, 2020 - Elsevier
Nervous necrosis virus (NNV) reassortant strains RGNNV/SJNNV have emerged as a potent
threat to the Mediterranean marine aquaculture industry, causing viral encephalopathy and …