Prebiotic peptides: Molecular hubs in the origin of life
The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …
Chemistry of abiotic nucleotide synthesis
The chemistry of abiotic nucleotide synthesis of RNA and DNA in the context of their
prebiotic origins on early earth is a continuing challenge. How did (or how can) the …
prebiotic origins on early earth is a continuing challenge. How did (or how can) the …
[HTML][HTML] The emergence of life
The aim of this article is to provide the reader with an overview of the different possible
scenarios for the emergence of life, to critically assess them and, according to the …
scenarios for the emergence of life, to critically assess them and, according to the …
Rolling circle RNA synthesis catalyzed by RNA
RNA-catalyzed RNA replication is widely considered a key step in the emergence of life's
first genetic system. However, RNA replication can be impeded by the extraordinary stability …
first genetic system. However, RNA replication can be impeded by the extraordinary stability …
Ribozyme-mediated RNA synthesis and replication in a model Hadean microenvironment
Enzyme-catalyzed replication of nucleic acid sequences is a prerequisite for the survival and
evolution of biological entities. Before the advent of protein synthesis, genetic information …
evolution of biological entities. Before the advent of protein synthesis, genetic information …
Ribozyme activity modulates the physical properties of RNA–peptide coacervates
Condensed coacervate phases are now understood to be important features of modern cell
biology, as well as valuable protocellular models in origin-of-life studies and synthetic …
biology, as well as valuable protocellular models in origin-of-life studies and synthetic …
Stranger than we can imagine: the possibility and potential significance of non-human forms of consciousness and wellbeing
T Lomas - The Journal of Positive Psychology, 2023 - Taylor & Francis
Recent decades have seen a flourishing of scholarship on wellbeing. Looking ahead, the
next frontier may be engaging with the possibility of non-human forms of wellbeing. This …
next frontier may be engaging with the possibility of non-human forms of wellbeing. This …
Origin of life: Drawing the big picture
F Prosdocimi, ST de Farias - Progress in Biophysics and Molecular Biology, 2023 - Elsevier
Trying to provide a broad overview about the origin of life in Earth, the most significant
transitions of life before cells are listed and discussed. The current approach emphasizes …
transitions of life before cells are listed and discussed. The current approach emphasizes …
Prebiotic phosphorylation and concomitant oligomerization of deoxynucleosides to form DNA
EI Jiménez, C Gibard… - Angewandte Chemie …, 2021 - Wiley Online Library
Recent demonstrations of RNA–DNA chimeras (RDNA) enabling RNA and DNA replication,
coupled with prebiotic co‐synthesis of deoxyribo‐and ribo‐nucleotides, have resurrected the …
coupled with prebiotic co‐synthesis of deoxyribo‐and ribo‐nucleotides, have resurrected the …
Enhanced ribozyme‐catalyzed recombination and oligonucleotide assembly in peptide‐RNA condensates
The ability of RNA to catalyze RNA ligation is critical to its central role in many prebiotic
model scenarios, in particular the copying of information during self‐replication. Prebiotically …
model scenarios, in particular the copying of information during self‐replication. Prebiotically …