Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine

J Nijs, SZ George, DJ Clauw… - The Lancet …, 2021 - thelancet.com
Chronic pain is a leading cause of disability globally and associated with enormous health-
care costs. The discrepancy between the extent of tissue damage and the magnitude of …

Persistent physical symptoms: definition, genesis, and management

B Löwe, A Toussaint, JGM Rosmalen, WL Huang… - The Lancet, 2024 - thelancet.com
Persistent physical symptoms (synonymous with persistent somatic symptoms) is an
umbrella term for distressing somatic complaints that last several months or more …

EULAR revised recommendations for the management of fibromyalgia

GJ Macfarlane, C Kronisch, LE Dean, F Atzeni… - Annals of the rheumatic …, 2017 - Elsevier
Abstract Objective The original European League Against Rheumatism recommendations
for managing fibromyalgia assessed evidence up to 2005. The paucity of studies meant that …

Chronic pain and mental health disorders: shared neural mechanisms, epidemiology, and treatment

WM Hooten - Mayo Clinic Proceedings, 2016 - Elsevier
Chronic pain and mental health disorders are common in the general population, and
epidemiological studies suggest that a bidirectional relationship exists between these 2 …

Fibromyalgia

W Häuser, J Ablin, MA Fitzcharles, G Littlejohn… - Nature reviews Disease …, 2015 - nature.com
Fibromyalgia is a common illness characterized by chronic widespread pain, sleep
problems (including unrefreshing sleep), physical exhaustion and cognitive difficulties. The …

Management of functional somatic syndromes and bodily distress

P Henningsen, S Zipfel, H Sattel, F Creed - Psychotherapy and …, 2018 - karger.com
Functional somatic syndromes (FSS), like irritable bowel syndrome or fibromyalgia and other
symptoms reflecting bodily distress, are common in practically all areas of medicine …

Interpretation of random effects meta-analyses

RD Riley, JPT Higgins, JJ Deeks - Bmj, 2011 - bmj.com
Interpretation of random effects meta-analyses | The BMJ Skip to main content Intended for
healthcare professionals Access provided by Google Indexer Subscribe My Account My email …

Fibromyalgia syndrome: etiology, pathogenesis, diagnosis, and treatment

E Bellato, E Marini, F Castoldi… - Pain research and …, 2012 - Wiley Online Library
Fibromyalgia syndrome is mainly characterized by pain, fatigue, and sleep disruption. The
etiology of fibromyalgia is still unclear: if central sensitization is considered to be the main …

[HTML][HTML] Tricyclic antidepressants

J Moraczewski, AO Awosika, KK Aedma - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Tricyclic Antidepressants - StatPearls - NCBI Bookshelf Your browser does not support the NLM
PubReader view. Go to this page to see a list of supported browsers or return to the regular …

Long-term consequences of chronic pain: mounting evidence for pain as a neurological disease and parallels with other chronic disease states

PG Fine - Pain medicine, 2011 - academic.oup.com
Objective. This article reviews the potential physical and psychological consequences of
chronic pain and the importance of implementing effective therapeutic strategies to mitigate …