Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials
Realization of the immense potential of nanomaterials for biomedical applications will
require a thorough understanding of how they interact with cells, tissues, and organs. There …
require a thorough understanding of how they interact with cells, tissues, and organs. There …
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
E Fröhlich - International journal of nanomedicine, 2012 - Taylor & Francis
Many types of nanoparticles (NPs) are tested for use in medical products, particularly in
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
imaging and gene and drug delivery. For these applications, cellular uptake is usually a …
Mesoporous silica nanoparticles: synthesis, pharmaceutical applications, biodistribution, and biosafety assessment
Mesoporous silica nanoparticles (MSNs) are a key example of the innovation in material
science to develop nanotechnology-based delivery systems. Biological and pharmaceutical …
science to develop nanotechnology-based delivery systems. Biological and pharmaceutical …
Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome
Objective Western lifestyle and diet are major environmental factors playing a role in the
development of IBD. Titanium dioxide (TiO2) nanoparticles are widely used as food …
development of IBD. Titanium dioxide (TiO2) nanoparticles are widely used as food …
Understanding nanoparticle cellular entry: a physicochemical perspective
CM Beddoes, CP Case, WH Briscoe - Advances in colloid and interface …, 2015 - Elsevier
Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …
cells, is becoming increasingly important due to their growing application in medicine and …
[HTML][HTML] In vitro approaches to assess the hazard of nanomaterials
B Drasler, P Sayre, KG Steinhäuser, A Petri-Fink… - NanoImpact, 2017 - Elsevier
The rapid development of engineered nanomaterials demands for a fast and reliable
assessment of their health hazard potential. A plethora of experimental approaches have …
assessment of their health hazard potential. A plethora of experimental approaches have …
Re‐evaluation of silicon dioxide (E 551) as a food additive
EFSA Panel on Food Additives and Nutrient … - Efsa …, 2018 - Wiley Online Library
Abstract The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
provides a scientific opinion re‐evaluating the safety of silicon dioxide (E 551) when used as …
provides a scientific opinion re‐evaluating the safety of silicon dioxide (E 551) when used as …
Direct chemical grafted curcumin on halloysite nanotubes as dual-responsive prodrug for pharmacological applications
Covalently functionalized halloysite nanotubes (HNTs) were successfully employed as dual-
responsive nanocarriers for curcumin (Cur). Particularly, we synthesized HNT-Cur prodrug …
responsive nanocarriers for curcumin (Cur). Particularly, we synthesized HNT-Cur prodrug …
Cellular targets and mechanisms in the cytotoxic action of non-biodegradable engineered nanoparticles
E Frohlich - Current drug metabolism, 2013 - benthamdirect.com
The use of nanoparticles (NPs) has improved the quality of many industrial, pharmaceutical,
and medical products. Increased surface reactivity, a major reason for the positive effects of …
and medical products. Increased surface reactivity, a major reason for the positive effects of …
Genotoxicity assessment of nanomaterials: recommendations on best practices, assays, and methods
R Elespuru, S Pfuhler, MJ Aardema… - Toxicological …, 2018 - academic.oup.com
Nanomaterials (NMs) present unique challenges in safety evaluation. An international
working group, the Genetic Toxicology Technical Committee of the International Life …
working group, the Genetic Toxicology Technical Committee of the International Life …