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Norepinephrine, neurodevelopment and behavior
Neurotransmitters play critical roles in the develo** nervous system. Among the
neurotransmitters, norepinephrine (NE) is in particular postulated to be an important …
neurotransmitters, norepinephrine (NE) is in particular postulated to be an important …
Locus ceruleus norepinephrine release: a central regulator of CNS spatio-temporal activation?
Norepinephrine (NE) is synthesized in the Locus Coeruleus (LC) of the brainstem, from
where it is released by axonal varicosities throughout the brain via volume transmission. A …
where it is released by axonal varicosities throughout the brain via volume transmission. A …
Two types of locus coeruleus norepinephrine neurons drive reinforcement learning
The cerebral cortex generates flexible behavior by learning. Reinforcement learning is
thought to be driven by error signals in midbrain dopamine neurons. However, they project …
thought to be driven by error signals in midbrain dopamine neurons. However, they project …
Central respiratory chemoreception
Brain PCO 2 is sensed primarily via changes in [H+]. Small pH changes are detected in the
medulla oblongata and trigger breathing adjustments that help maintain arterial PCO 2 …
medulla oblongata and trigger breathing adjustments that help maintain arterial PCO 2 …
Noradrenergic cross-modular reciprocal inhibition within the locus coeruleus
Abstract The Locus Coeruleus (LC) is the primary noradrenergic nucleus in the brain with
widespread projections driving changes in cognitive state and animal behaviour. The LC is …
widespread projections driving changes in cognitive state and animal behaviour. The LC is …
[HTML][HTML] The FitzHugh-Nagumo Equations and Quantum Noise
P Ghose, DA Pinotsis - Computational and Structural Biotechnology Journal, 2025 - Elsevier
It is unclear whether quantum phenomena can be observed in brain recordings because of
thermal noise causing decoherence, that is, quantum superpositions and entanglement …
thermal noise causing decoherence, that is, quantum superpositions and entanglement …
Unraveling the functional complexity of the locus coeruleus-norepinephrine system: insights from molecular anatomy to neurodynamic modeling
CW Su, F Yang, R Lai, Y Li, H Naeem, N Yao… - Cognitive …, 2025 - Springer
The locus coeruleus (LC), as the primary source of norepinephrine (NE) in the brain, is
central to modulating cognitive and behavioral processes. This review synthesizes recent …
central to modulating cognitive and behavioral processes. This review synthesizes recent …
[HTML][HTML] Autocrine neuromodulation and network activity patterns in the locus coeruleus of newborn rat slices
Q Waselenchuk, K Ballanyi - Brain Sciences, 2022 - mdpi.com
Already in newborns, the locus coeruleus (LC) controls multiple brain functions and may
have a complex organization as in adults. Our findings in newborn rat brain slices indicate …
have a complex organization as in adults. Our findings in newborn rat brain slices indicate …
Role of the locus coeruleus in the emergence of power law wake bouts in a model of the brainstem sleep-wake system through early infancy
M Patel, A Rangan - Journal of Theoretical Biology, 2017 - Elsevier
Infant rats randomly cycle between the slee** and waking states, which are tightly
correlated with the activity of mutually inhibitory brainstem sleep and wake populations …
correlated with the activity of mutually inhibitory brainstem sleep and wake populations …
Development of the sleep-wake switch in rats during the P2-P21 early infancy period
M Patel, B Joshi - Frontiers in Network Physiology, 2024 - frontiersin.org
In early infancy, rats randomly alternate between the slee** and waking states–from
postnatal day 2–10 (P2-P10), sleep and wake bouts are both exponentially distributed with …
postnatal day 2–10 (P2-P10), sleep and wake bouts are both exponentially distributed with …