Norepinephrine, neurodevelopment and behavior

E Saboory, M Ghasemi, N Mehranfard - Neurochemistry international, 2020 - Elsevier
Neurotransmitters play critical roles in the develo** nervous system. Among the
neurotransmitters, norepinephrine (NE) is in particular postulated to be an important …

Locus ceruleus norepinephrine release: a central regulator of CNS spatio-temporal activation?

M Atzori, R Cuevas-Olguin… - Frontiers in synaptic …, 2016 - frontiersin.org
Norepinephrine (NE) is synthesized in the Locus Coeruleus (LC) of the brainstem, from
where it is released by axonal varicosities throughout the brain via volume transmission. A …

Two types of locus coeruleus norepinephrine neurons drive reinforcement learning

Z Su, JY Cohen - BioRxiv, 2022 - biorxiv.org
The cerebral cortex generates flexible behavior by learning. Reinforcement learning is
thought to be driven by error signals in midbrain dopamine neurons. However, they project …

Central respiratory chemoreception

PG Guyenet, DA Bayliss - Handbook of clinical neurology, 2022 - Elsevier
Brain PCO 2 is sensed primarily via changes in [H+]. Small pH changes are detected in the
medulla oblongata and trigger breathing adjustments that help maintain arterial PCO 2 …

Noradrenergic cross-modular reciprocal inhibition within the locus coeruleus

O Davy, R Perrins, M Lavigne, E Kremer… - bioRxiv, 2022 - biorxiv.org
Abstract The Locus Coeruleus (LC) is the primary noradrenergic nucleus in the brain with
widespread projections driving changes in cognitive state and animal behaviour. The LC is …

[HTML][HTML] The FitzHugh-Nagumo Equations and Quantum Noise

P Ghose, DA Pinotsis - Computational and Structural Biotechnology Journal, 2025 - Elsevier
It is unclear whether quantum phenomena can be observed in brain recordings because of
thermal noise causing decoherence, that is, quantum superpositions and entanglement …

Unraveling the functional complexity of the locus coeruleus-norepinephrine system: insights from molecular anatomy to neurodynamic modeling

CW Su, F Yang, R Lai, Y Li, H Naeem, N Yao… - Cognitive …, 2025 - Springer
The locus coeruleus (LC), as the primary source of norepinephrine (NE) in the brain, is
central to modulating cognitive and behavioral processes. This review synthesizes recent …

[HTML][HTML] Autocrine neuromodulation and network activity patterns in the locus coeruleus of newborn rat slices

Q Waselenchuk, K Ballanyi - Brain Sciences, 2022 - mdpi.com
Already in newborns, the locus coeruleus (LC) controls multiple brain functions and may
have a complex organization as in adults. Our findings in newborn rat brain slices indicate …

Role of the locus coeruleus in the emergence of power law wake bouts in a model of the brainstem sleep-wake system through early infancy

M Patel, A Rangan - Journal of Theoretical Biology, 2017 - Elsevier
Infant rats randomly cycle between the slee** and waking states, which are tightly
correlated with the activity of mutually inhibitory brainstem sleep and wake populations …

Development of the sleep-wake switch in rats during the P2-P21 early infancy period

M Patel, B Joshi - Frontiers in Network Physiology, 2024 - frontiersin.org
In early infancy, rats randomly alternate between the slee** and waking states–from
postnatal day 2–10 (P2-P10), sleep and wake bouts are both exponentially distributed with …