Background The effectiveness of high-flow nasal cannula oxygen therapy (HFNC) in
patients with acute respiratory failure due to COVID-19 remains uncertain. We aimed at …

Background Several recently published randomized controlled trials have evaluated various
noninvasive oxygenation strategies for the treatment of acute hypoxemic respiratory failure …

Background The risk of barotrauma associated with different types of ventilatory support is
unclear in COVID-19 patients. The primary aim of this study was to evaluate the effect of the …

Introduction Although largely used, the place of oxygen therapy and its devices in patients
with acute hypoxemic respiratory failure (ARF) deserves to be clarified. The French Intensive …

Background Noninvasive methods of respiratory support, including noninvasive ventilation
(NIV), continuous positive airway pressure (CPAP), and high-flow nasal oxygen (HFNO), are …

High-flow nasal therapy (HFNT) provides several pathophysiological benefits in chronic
respiratory disorders. We aimed to evaluate the effectiveness of long-term HFNT in patients …

Background Benefit of early awake prone positioning for COVID-19 patients hospitalised in
medical wards and who need oxygen therapy remains to be demonstrated. The question …

OBJECTIVE: High-flow nasal oxygen (HFNO) therapy is frequently applied outside ICU
setting in hypoxemic patients with COVID-19. However, safety concerns limit more …

Acute respiratory failure is a common reason for emergency department visits and hospital
admissions. Diverse underlying physiologic abnormalities lead to unique aspects about the …

Acute respiratory failure due to COVID-19 pneumonia often requires a comprehensive
approach that includes non-pharmacological strategies such as non-invasive support …