Idiopathic pulmonary fibrosis (IPF) is a progressive, and ultimately fatal, chronic interstitial
lung disease characterized by enhanced extracellular matrix deposition. Repetitive alveolar …

In the classic Cyclic guanosine monophosphate–adenosine monophosphate (cGAMP)
synthase (cGAS)-stimulator of interferon genes (STING) pathway, downstream signals can …

Innate immunity is regulated by a broad set of evolutionary conserved receptors to finely
probe the local environment and maintain host integrity. Besides pathogen recognition …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive scarring interstitial lung disease
with an unknown cause. Some patients may experience acute exacerbations (AE), which …

Since cyclic guanosine monophosphate‐adenosine monophosphate synthase (cGAS)–
stimulator of interferon genes (STING) signaling pathway was discovered in 2013, great …

Background. Acute exacerbation of IPF (AE‐IPF) is associated with high mortality. We
studied changes in pathogen involvement during AE‐IPF and explored a possible role of …

Pulmonary fibrosis (PF) is a chronic interstitial lung disease with unknown etiology. In the
present study, we evaluated the anti-fibrotic effects of heterophyllin B, a natural product from …

Idiopathic pulmonary fibrosis (IPF), characterized by excessive collagen deposition, is a
progressive and typically fatal lung disease without effective therapeutic strategies. Juglanin …

Background: Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) has a poor
prognosis and lacks effective therapy. Animal models that mimic AE-IPF can greatly …

Idiopathic pulmonary fibrosis (IPF) and other forms of lung fibrosis are age-associated
diseases with increased deposition of mesenchymal collagen that promotes respiratory …