Benign prostatic hyperplasia (BPH) is a common chronic disease in older males. The
pathogenesis of BPH remains elusive but may be associated with chronic inflammation …

Background Inflammatory and inducible chemokines are the hallmarks of malignancy.
Monocyte chemo-attractant protein-1 (MCP-1) is a crucial chemokine implicated in infection …

Genetic susceptibility has been described in insulin resistance (IR). Chemokine (C‐C motif)
ligand‐2 (CCL2) is overexpressed in white adipose tissue and is the ligand of C‐C motif …

BACKGROUND AND OBJECTIVES: The role of CCR2-V64I polymorphism in various
cancers has been reported in many studies. However, results from published studies on the …

Studies investigating the impact of polymorphisms on monocyte chemotactic protein-1 (MCP-
1) and CC chemokine receptor 2 (CCR2) on the risk of cancer have reported inconsistent …

Chemokines and their receptors acts as mediators of migration of immune cells to the site of
inflammation and deregulated inflammatory response is associated with increased risk of …

Single nucleotide polymorphism (SNPs) in genes coding for chemokines may be associated
with some cancer. The purpose of this study was to investigate the impact of CCR2-64I and …

BACKGROUND AND AIM: p73, a novel P53 homolog and plays an important role in
modulating cell cycle control, apoptosis and cell growth while P21, functions to negatively …

Background Single nucleotide polymorphisms (SNPs) may affect the development of
diseases. The-2518A/G polymorphism in the regulatory region of the monocyte chemo …

Bladder cancer (BCa) is one of the most frequent urogenital malignancies which is mainly
observed among men. There are various genetic and environmental risk factors associated …