The development of organometallic catalysis has greatly expanded the synthetic chemist
toolbox compared to only exploiting “classical” organic chemistry. Although more widely …

The importance of transition metal catalysis is exemplified by its wide range of applications,
for example in the synthesis of chemicals, natural products, and pharmaceuticals. However …

State-of-the-art photoactivation strategies in chemical biology provide spatiotemporal control
and visualization of biological processes. However, using high-energy light (λ< 500 nm) for …

Light-powered catalysis has found broad utility as a chemical transformation strategy, with
widespread impact on energy, environment, drug discovery and human health. A noteworthy …

The catalysis of bioorthogonal transformations inside living organisms is a formidable
challenge—yet bears great potential for future applications in chemical biology and …

Spatiotemporally resolved dissection of subcellular proteome is crucial to our understanding
of cellular functions in health and disease. We herein report a bioorthogonal and …

The field of bioorthogonal chemistry has revolutionized our ability to interrogate and
manipulate biological systems at the molecular level. However, the range of chemical …

Combining synthetic chemistry and biocatalysis is a promising but underexplored approach
to intracellular catalysis. We report a strategy to codeliver a single-chain nanoparticle …

Here, we report a visible-light-induced deboronative alkynylation reaction, which is redox-
neutral and works with primary, secondary and tertiary alkyl trifluoroborates or boronic acids …

An emerging approach in the field of targeted drug delivery is the establishment of abiotic
metal‐triggered prodrug mechanisms that can control the release of bioactive drugs …