This 2023 statement updates clinical guidance for homozygous familial
hypercholesterolaemia (HoFH), explains the genetic complexity, and provides pragmatic …

Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

This contemporary, international, evidence-informed guidance aims to achieve the greatest
good for the greatest number of people with familial hypercholesterolaemia (FH) across …

version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Cardiovascular disease (CVD) is still a leading cause of morbidity and mortality, despite all
the progress achieved as regards to both prevention and treatment. Having high levels of …

Lipid disorders involving derangements in serum cholesterol, triglycerides, or both are
commonly encountered in clinical practice and often have implications for cardiovascular …

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban
and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a …

Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been
considered as a high-risk factor and key indicator of many metabolic diseases. The gut …

Summary Background Homozygous familial hypercholesterolaemia (HoFH) is a rare
inherited disorder resulting in extremely elevated low-density lipoprotein cholesterol levels …

Atherosclerotic cardiovascular disease is the leading cause of death globally. Despite its
important risk of premature atherosclerosis and cardiovascular disease, familial …