Resistance threatens to render antibiotics—which are essential for modern medicine—
ineffective, thus posing a threat to human health. The discovery of novel classes of …

The CRISPR system is a revolutionary genome editing tool that has the potential to
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …

Antibiotic treatments have detrimental effects on the microbiome and lead to antibiotic
resistance. To develop a phage therapy against a diverse range of clinically relevant …

According to Darwin's theory, endless evolution leads to a revolution. One such example is
the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an …

The term 'clustered regularly interspaced short palindromic repeats'(CRISPR) has recently
become synonymous with the genome-editing revolution. The RNA-guided endonuclease …

Antibiotic resistance threatens our ability to treat infectious diseases, spurring interest in
alternative antimicrobial technologies. The use of bacterial conjugation to deliver CRISPR …

The innovation of new therapies to combat multidrug-resistant (MDR) bacteria is being
outpaced by the continued rise of MDR bacterial infections. Of particular concern are …

The alarming rise in antimicrobial resistance coupled with a lack of innovation in antibiotics
has renewed interest in the development of alternative therapies to combat bacterial …

Having co-evolved with bacteria over hundreds of millions of years, bacteriophage are
effective killers of specific bacterial hosts. Therefore, phage therapies for infection are a …

Bacteriophages are pervasive viruses that infect bacteria, relying on their genetic machinery
to replicate. In order to protect themselves from this kind of invader, bacteria developed an …