Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

The basal ganglia and the cerebellum are considered to be distinct subcortical systems that
perform unique functional operations. The outputs of the basal ganglia and the cerebellum …

Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

Multiple surgical targets for treating obsessive-compulsive disorder with deep brain
stimulation (DBS) have been proposed. However, different targets may modulate the same …

Classically, the basal ganglia have been considered to have a role in producing habitual
and goal-directed behaviours. In this article, we review recent evidence that expands this …

Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

Deep brain stimulation (DBS) is an established and growing intervention for treatment-
resistant obsessive-compulsive disorder (TROCD). We assessed current evidence on the …

Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …