Moderately elevated plasma total homocysteine (tHcy) is a strong modifiable risk factor for
vascular dementia and Alzheimer's disease. Prospectively, elevated tHcy is associated with …

Aims/Hypothesis Accumulating evidence suggests an association between coronary heart
disease and risk for cognitive impairment or dementia, but no study has systematically …

Background Cardiovascular factors and low education are important risk factors of dementia.
We provide contemporary estimates of the proportion of dementia cases that could be …

Objective We aimed to examine whether impaired olfaction is associated with cognitive
decline and indicators of neurodegeneration in the brain of dementia-free older adults …

Central theories of cognitive aging propose that education is an important protective factor
for decline in cognitive performance in older age. We conducted a systematic review and …

Introduction Cardiovascular risk factors are closely linked with dementia risk, but whether
heart disease predisposes to dementia is uncertain. Methods We systematically reviewed …

Importance Previous research has suggested an association of kidney function with risk of
Alzheimer disease (AD) or other dementias and dementia-related blood biomarkers, but a …

The Diagnostic Statistical Manual-5 (DSM-5) has included a category named the
neurocognitive disorder which was formally known in DSM-IV as 'dementia, delirium …

Objective Community-based reports regarding the association between the estimated
glomerular filtration rate (eGFR) and dementia risk show conflicting results. The aim of this …

Background Living alone may be associated with greater risk for social isolation and
loneliness. Living alone, social isolation, loneliness, and limited engagement in social …