A comprehensive and system review for the pharmacological mechanism of action of rhein, an active anthraquinone ingredient
H Sun, G Luo, D Chen, Z **ang - Frontiers in pharmacology, 2016 - frontiersin.org
Rhein is a major medicinal ingredient isolated from several traditional Chinese medicines,
including Rheum palmatum L., Aloe barbadensis Miller, Cassia angustifolia Vahl., and …
including Rheum palmatum L., Aloe barbadensis Miller, Cassia angustifolia Vahl., and …
[HTML][HTML] Cassia species: A review of traditional uses, phytochemistry and pharmacology
Cassia species have a long history of utilization in various traditional medicine systems
worldwide, and they are widely consumed for medicinal purposes, particularly the officinal …
worldwide, and they are widely consumed for medicinal purposes, particularly the officinal …
Deoxycholic acid-functionalised nanoparticles for oral delivery of rhein
W Yao, Z Xu, J Sun, J Luo, Y Wei, J Zou - European Journal of …, 2021 - Elsevier
Rhein (RH) is a candidate for the treatment of kidney diseases. However, clinical application
of RH is impeded by low aqueous solubility and oral bioavailability. Deoxycholic acid …
of RH is impeded by low aqueous solubility and oral bioavailability. Deoxycholic acid …
Secretory clusterin promotes oral cancer cell survival via inhibiting apoptosis by activation of autophagy in AMPK/mTOR/ULK1 dependent pathway
Aims Secretory clusterin (sCLU) plays an important role in tumor development and cancer
progression. However, the molecular mechanisms and physiological functions of sCLU in …
progression. However, the molecular mechanisms and physiological functions of sCLU in …
Waterless Dyeing and In Vitro Toxicological Properties of Biocolorants from Cortinarius sanguineus
M Herrala, J Yli-Öyrä, AF de Albuquerque… - Journal of Fungi, 2022 - mdpi.com
As a part of an ongoing interest in identifying environmentally friendly alternatives to
synthetic dyes and in using liquid CO2 as a waterless medium for applying the resulting …
synthetic dyes and in using liquid CO2 as a waterless medium for applying the resulting …
Rhein reverses doxorubicin resistance in SMMC‐7721 liver cancer cells by inhibiting energy metabolism and inducing mitochondrial permeability transition pore …
L Wu, K Cao, Z Ni, S Wang, W Li, X Liu, Z Chen - Biofactors, 2019 - Wiley Online Library
Rhein, a monomeric anthraquinone obtained from the plant herb species Polygonum
multiflorum and P. cuspidatum, has been proposed to have anticancer activity. This activity …
multiflorum and P. cuspidatum, has been proposed to have anticancer activity. This activity …
Toxicity of naturally occurring anthraquinones
Among the vast array of secondary metabolites produced by plants, anthraquinones (AQs)
are the group of compounds produced by different plants of various families such as …
are the group of compounds produced by different plants of various families such as …
Liver toxicity of anthraquinones: A combined in vitro cytotoxicity and in silico reverse dosimetry evaluation
Y Liu, MST Mapa, RL Sprando - Food and Chemical Toxicology, 2020 - Elsevier
Anthraquinones are found in a variety of consumer products such as dietary supplements,
traditional Chinese medicines, and drugs. Along with their widespread use, potential safety …
traditional Chinese medicines, and drugs. Along with their widespread use, potential safety …
Simulation study of the pH sensitive directed self-assembly of rheins for sustained drug release hydrogel
YH Feng, XP Zhang, YY Hao, GY Ren… - Colloids and Surfaces B …, 2020 - Elsevier
The hydrogel formed by the directed self-assembled rhein molecules at an appropriate pH
value for sustained drug release has been reported recently. Although the application in …
value for sustained drug release has been reported recently. Although the application in …
Insights into the modulatory role of cyclosporine A and its research advances in acute inflammation
Q Gui, Z Jiang, L Zhang - International Immunopharmacology, 2021 - Elsevier
Cyclosporine A (CsA), a classic immunosuppressant, is mainly applied for solid organ
transplantation and some autoimmune diseases by suppressing T lymphocytes. Early …
transplantation and some autoimmune diseases by suppressing T lymphocytes. Early …