Pleiotropy and specificity: insights from the interleukin 6 family of cytokines
Since the molecular cloning of interleukin-6 (IL-6) in 1986, many other cytokines have been
found to share the same signal transducer, gp130, in their receptor complexes. Thus, the IL …
found to share the same signal transducer, gp130, in their receptor complexes. Thus, the IL …
Tissue engineering for clean meat production
T Ben-Arye, S Levenberg - Frontiers in Sustainable Food Systems, 2019 - frontiersin.org
Increasing public awareness of foodborne illnesses, factory farming, and the ecological
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …
A targetable LIFR− NF-κB− LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
The growing knowledge of ferroptosis has suggested the role and therapeutic potential of
ferroptosis in cancer, but has not been translated into effective therapy. Liver cancer …
ferroptosis in cancer, but has not been translated into effective therapy. Liver cancer …
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis largely owing to
inefficient diagnosis and tenacious drug resistance. Activation of pancreatic stellate cells …
inefficient diagnosis and tenacious drug resistance. Activation of pancreatic stellate cells …
LIF signaling regulates outer radial glial to interneuron fate during human cortical development
Radial glial (RG) development is essential for cerebral cortex growth and organization. In
humans, the outer radial glia (oRG) subtype is expanded and gives rise to diverse neurons …
humans, the outer radial glia (oRG) subtype is expanded and gives rise to diverse neurons …
Sarcopenia and cognitive function: role of myokines in muscle brain cross-talk
L Scisciola, RA Fontanella, Surina, V Cataldo… - Life, 2021 - mdpi.com
Sarcopenia is a geriatric syndrome characterized by the progressive degeneration of muscle
mass and function, and it is associated with severe complications, which are falls, functional …
mass and function, and it is associated with severe complications, which are falls, functional …
STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis
WH Lin, YW Chang, MX Hong, TC Hsu, KC Lee, C Lin… - Oncogene, 2021 - nature.com
Abstract Epithelial–mesenchymal transition (EMT)/mesenchymal–epithelial transition (MET)
processes are proposed to be a driving force of cancer metastasis. By studying metastasis in …
processes are proposed to be a driving force of cancer metastasis. By studying metastasis in …
Progesterone as an anti-inflammatory drug and immunomodulator: new aspects in hormonal regulation of the inflammation
TA Fedotcheva, NI Fedotcheva, NL Shimanovsky - Biomolecules, 2022 - mdpi.com
The specific regulation of inflammatory processes by steroid hormones has been actively
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …
studied in recent years, especially by progesterone (P4) and progestins. The mechanisms of …
Development of a Chemically Defined Medium for in vitro Expansion of Primary Bovine Satellite Cells
AM Kolkmann, A Van Essen, MJ Post… - … in bioengineering and …, 2022 - frontiersin.org
The use of fetal bovine serum (FBS) in animal cell culture media is widely spread since it
provides a broad spectrum of molecules that are known to support cell attachment and …
provides a broad spectrum of molecules that are known to support cell attachment and …
The role of interleukin-6 family members in cardiovascular diseases
Y Feng, D Ye, Z Wang, H Pan, X Lu, M Wang… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …