Redox reactions catalyzed by isolated enzymes
D Monti, G Ottolina, G Carrea, S Riva - Chemical reviews, 2011 - ACS Publications
The class of oxidoreductases, to which belong all enzymes catalyzing oxidoreduction
reactions, includes several groups of biocatalysts such as dehydrogenases …
reactions, includes several groups of biocatalysts such as dehydrogenases …
The role of biocatalysis in the asymmetric synthesis of alkaloids
JH Schrittwieser, V Resch - RSC advances, 2013 - pubs.rsc.org
Alkaloids are not only one of the most intensively studied classes of natural products, their
wide spectrum of pharmacological activities also makes them indispensable drug …
wide spectrum of pharmacological activities also makes them indispensable drug …
Biocatalytic applications
K Faber, K Faber - Biotransformations in organic chemistry: a textbook, 2018 - Springer
Of all the types of enzyme-catalyzed reactions, hydrolytic transformations involving amide
and ester bonds are the easiest to perform using proteases, esterases, or lipases. The key …
and ester bonds are the easiest to perform using proteases, esterases, or lipases. The key …
Crystal structure of bacterial morphinone reductase and properties of the C191A mutant enzyme
The crystal structure of the NADH-dependent bacterial flavoenzyme morphinone reductase
(MR) has been determined at 2.2-Å resolution in complex with the oxidizing substrate …
(MR) has been determined at 2.2-Å resolution in complex with the oxidizing substrate …
Engineering novel biocatalytic routes for production of semisynthetic opiate drugs
The morphine alkaloids and their semisynthetic derivatives provide a diverse range of
important pharmaceutical drugs. Current production of semisynthetic opiate drugs is by …
important pharmaceutical drugs. Current production of semisynthetic opiate drugs is by …
Transformations of codeine to important semisynthetic opiate derivatives by Pseudomonas putida m10
A biotransformation mixture which contained codeine and washed cells of Pseudomonas
putida M10 gave rise to a number of transformation products that are of clinical importance …
putida M10 gave rise to a number of transformation products that are of clinical importance …
Reductive and Oxidative Half-Reactions of Morphinone Reductase from Pseudomonas putida M10: A Kinetic and Thermodynamic Analysis
The reaction of morphinone reductase (MR) with the physiological reductant NADH and the
oxidizing substrate codeinone has been studied by multiple and single wavelength stopped …
oxidizing substrate codeinone has been studied by multiple and single wavelength stopped …
Biotransformation of codeine to morphine in freely suspended cells and immobilized cultures of Spirulina platensis
S Ramachandra Rao, U Tripathi… - World Journal of …, 1999 - Springer
Both freely suspended cells and immobilized cultures of Spirulina platensis, a blue-green
alga, biotransformed exogenously fed codeine, an opium alkaloid, to morphine. The external …
alga, biotransformed exogenously fed codeine, an opium alkaloid, to morphine. The external …
Reaction of morphinone reductase with 2-cyclohexen-1-one and 1-nitrocyclohexene: proton donation, ligand binding, and the role of residues Histidine 186 and …
Morphinone reductase (MR) catalyzes the NADH-dependent reduction of α/β unsaturated
carbonyl compounds in a reaction similar to that catalyzed by Old Yellow Enzyme (OYE1) …
carbonyl compounds in a reaction similar to that catalyzed by Old Yellow Enzyme (OYE1) …
Towards an efficient preparation of hydromorphone
R Csuk, G Vasileva, A Barthel - Synthesis, 2012 - thieme-connect.com
Thieme E-Journals - Synthesis / Full Text DE EN Home Products Journals Books Book Series
Service Library Service Help Contact Portal SYNTHESIS Full-text search Full-text search …
Service Library Service Help Contact Portal SYNTHESIS Full-text search Full-text search …