Computational neuroscience has come a long way from its humble origins in the pioneering
work of Hodgkin and Huxley. Contemporary computational models of the brain span multiple …

Background The g-ratio, quantifying the comparative thickness of the myelin sheath
encasing an axon, is a geometrical invariant that has high functional relevance because of …

The conduction velocity (CV) of action potentials along axons is a key neurophysiological
property central to neural communication. The ability to estimate CV in humans in vivo from …

The neuronal differences contributing to the etiology of autism spectrum disorder (ASD) are
still not well defined. Previous studies have suggested that myelin and axons are disrupted …

Conduction velocity is the speed at which electrical signals travel along axons and is a
crucial determinant of neural communication. Inferences about conduction velocity can now …

Objective The ability to selectively up-or downregulate interregional brain connectivity would
be useful for research and clinical purposes. Toward this aim, cortico-cortical paired …

Assessing axonal morphology in vivo opens new avenues for the combined study of brain
structure and function. A novel approach has recently been introduced to estimate the …

In patients with retinal ganglion cell diseases, recent diffusion tensor imaging (DTI) studies
have revealed structural abnormalities in visual white matter tracts such as the optic tract …

Myelin plays a crucial role in how well information travels between brain regions.
Complementing the structural connectome, obtained with diffusion MRI tractography, with a …

In developed countries, multiple sclerosis (MS) is the leading cause of non-traumatic
neurological disability in young adults. MS is a chronic demyelinating disease of the central …