Sex differences in biological aging with a focus on human studies

S Hägg, J Jylhävä - elife, 2021 - elifesciences.org
Aging is a complex biological process characterized by hallmark features accumulating over
the life course, sha** the individual's aging trajectory and subsequent disease risks. There …

Telomere length as a marker of biological age: state-of-the-art, open issues, and future perspectives

A Vaiserman, D Krasnienkov - Frontiers in genetics, 2021 - frontiersin.org
Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …

Association between the oxidative balance score and telomere length from the National Health and Nutrition Examination Survey 1999‐2002

W Zhang, SF Peng, L Chen, HM Chen… - Oxidative medicine …, 2022 - Wiley Online Library
Purpose. Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …

[PDF][PDF] Inverse association of telomere length with liver disease and mortality in the US population

P Rattan, DD Penrice, JC Ahn, A Ferrer… - Hepatology …, 2022 - Wiley Online Library
Physiologic aging leads to attrition of telomeres and replicative senescence. An acceleration
of this process has been hypothesized in the progression of chronic liver disease. We …

Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up

X Li, A Ploner, Y Wang, PKE Magnusson, C Reynolds… - elife, 2020 - elifesciences.org
Biological age measurements (BAs) assess aging-related physiological change and predict
health risks among individuals of the same chronological age (CA). Multiple BAs have been …

Determination of biological age: geriatric assessment vs biological biomarkers

LWM Diebel, K Rockwood - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Biological age is the concept of using biophysiological
measures to more accurately determine an individual's age-related risk of adverse …

Levels of a mixture of heavy metals in blood and urine and all-cause, cardiovascular disease and cancer mortality: a population-based cohort study

W Duan, C Xu, Q Liu, J Xu, Z Weng, X Zhang… - Environmental …, 2020 - Elsevier
People are exposed to heavy metals in many ways during the course of their daily life.
However, the effect of mixtures of heavy metals on mortality in the US general population is …

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

RF Hillary, AJ Stevenson, DL McCartney… - Clinical …, 2020 - Springer
Background Individuals of the same chronological age display different rates of biological
ageing. A number of measures of biological age have been proposed which harness age …

Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

ND Saenen, DS Martens, KY Neven, R Alfano… - Clinical …, 2019 - Springer
Abstract According to the “Developmental Origins of Health and Disease”(DOHaD) concept,
the early-life environment is a critical period for fetal programming. Given the …

[HTML][HTML] Telomere length and brain aging: A systematic review and meta-analysis

P Gampawar, R Schmidt, H Schmidt - Ageing research reviews, 2022 - Elsevier
The current evidence on the association of leukocyte telomere length (LTL) with age-related
structural and cognitive changes in the brain is mixed. Herein conforming to PRISMA 2020 …