The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Pericytes are vascular mural cells embedded in the basement membrane of blood
microvessels. They extend their processes along capillaries, pre-capillary arterioles and …

Pericytes, the mural cells of blood microvessels, have recently come into focus as regulators
of vascular morphogenesis and function during development, cardiovascular homeostasis …

Interactions between endothelial cells and mural cells (pericytes and vascular smooth
muscle cells) in the blood vessel wall have recently come into focus as central processes in …

Mural cells are essential components of blood vessels and are necessary for normal
development, homeostasis, and organ function. Alterations in mural cell density or the stable …

In spite of the advances in the knowledge of adult stem cells (ASCs) during the past few
years, their natural activities in vivo are still poorly understood. Mesenchymal stem cells …

Ageing processes play a major contributing role for the development of Osteoarthritis (OA).
This prototypic degenerative condition of ageing is the most common form of arthritis and is …

The intracellular mechanism of transforming growth factor-β (TGFβ) signalling via kinase
receptors and SMAD effectors is firmly established, but recent studies of human …

We review the morphofunctional characteristics of pericytes and report our observations.
After a brief historical background, we consider the following aspects of pericytes: A) Origin …

The formation of new blood vessels is a crucial step in the development of any new tissue
both during embryogenesis and in vitro models as without sufficient perfusion the tissue will …