Functional lung imaging in radiation therapy for lung cancer: A systematic review and meta-analysis

NW Bucknell, N Hardcastle, M Bressel… - Radiotherapy and …, 2018 - Elsevier
Rationale Advanced imaging techniques allow functional information to be derived and
integrated into treatment planning. Methods A systematic review was conducted with the …

Functional image-guided radiotherapy planning for normal lung avoidance

RH Ireland, BA Tahir, JM Wild, CE Lee, MQ Hatton - Clinical Oncology, 2016 - Elsevier
For patients with lung cancer undergoing curative intent radiotherapy, functional lung
imaging can be incorporated into treatment planning to modify the dose distribution within …

The VAMPIRE challenge: a multi‐institutional validation study of CT ventilation imaging

J Kipritidis, BA Tahir, G Cazoulat, MS Hofman… - Medical …, 2019 - Wiley Online Library
Purpose CT ventilation imaging (CTVI) is being used to achieve functional avoidance lung
cancer radiation therapy in three clinical trials (NCT02528942, NCT02308709 …

Evaluating the toxicity reduction with computed tomographic ventilation functional avoidance radiation therapy

AM Faught, Y Miyasaka, N Kadoya, R Castillo… - International Journal of …, 2017 - Elsevier
Purpose Computed tomographic (CT) ventilation imaging is a new modality that uses 4-
dimensional (4D) CT information to calculate lung ventilation. Although retrospective studies …

A deep learning model for translating CT to ventilation imaging: analysis of accuracy and impact on functional avoidance radiotherapy planning

Z Hou, Y Kong, J Wu, J Gu, J Liu, S Gao, Y Yin… - Japanese Journal of …, 2024 - Springer
Purpose Radiotherapy planning incorporating functional lung images has the potential to
reduce pulmonary toxicity. Free-breathing 4DCT-derived ventilation image (CTVI) may help …

Innovations in thoracic imaging: CT, radiomics, AI and x‐ray velocimetry

R Vliegenthart, A Fouras, C Jacobs… - …, 2022 - Wiley Online Library
In recent years, pulmonary imaging has seen enormous progress, with the introduction,
validation and implementation of new hardware and software. There is a general trend from …

A hybrid model‐and deep learning‐based framework for functional lung image synthesis from multi‐inflation CT and hyperpolarized gas MRI

JR Astley, AM Biancardi, H Marshall… - Medical …, 2023 - Wiley Online Library
Background Hyperpolarized gas MRI is a functional lung imaging modality capable of
visualizing regional lung ventilation with exceptional detail within a single breath. However …

Imaging of regional ventilation: Is CT ventilation imaging the answer? A systematic review of the validation data

F Hegi-Johnson, D de Ruysscher, P Keall… - Radiotherapy and …, 2019 - Elsevier
Abstract Computed Tomography Ventilation Imaging (CTVI) is an experimental imaging
modality that derives regional lung function information from non-contrast respiratory …

Four-dimensional computed tomography ventilation image-guided lung functional avoidance radiation therapy: A single-arm prospective pilot clinical trial

T Yamamoto, S Kabus, M Bal, PJ Keall, A Moran… - International Journal of …, 2023 - Elsevier
Purpose The primary objective of this prospective pilot trial was to assess the safety and
feasibility of lung functional avoidance radiation therapy (RT) with 4-dimensional (4D) …

CT ventilation image-guided helical Tomotherapy at sparing functional lungs for locally advanced lung cancer: analysis of dose-function metrics and the impact on …

S Li, J Liu, S Gao, Y Yin, L Zhang, Y Han, X Zhang… - Radiation …, 2023 - Springer
Purpose CT ventilation image (CTVI)-guided radiotherapy that selectively avoids irradiating
highly-functional lung regions has potential to reduce pulmonary toxicity. Considering …