Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

The Vulnerable, or High-Risk, Atherosclerotic Plaque: Noninvasive MR Imaging for Characterization and Assessment1

T Saam, TS Hatsukami, N Takaya, B Chu, H Underhill… - Radiology, 2007 - pubs.rsna.org
“Vulnerable” plaques are atherosclerotic plaques that have a high likelihood to cause
thrombotic complications, such as myocardial infarction or stroke. Plaques that tend to …

Cardiovascular magnetic resonance

DJ Pennell - Circulation, 2010 - Am Heart Assoc
Cardiovascular magnetic resonance (CMR) creates images from atomic nuclei with uneven
spin using radiowaves in the presence of a magnetic field. Full details of the physical …

Peptide-based nanoprobes for molecular imaging and disease diagnostics

P Zhang, Y Cui, CF Anderson, C Zhang, Y Li… - Chemical Society …, 2018 - pubs.rsc.org
Pathological changes in a diseased site are often accompanied by abnormal activities of
various biomolecules in and around the involved cells. Identifying the location and …

Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications

DE Sosnovik, M Nahrendorf, R Weissleder - Basic research in cardiology, 2008 - Springer
Magnetic nanoparticles (MNP) are playing an increasingly important role in cardiovascular
molecular imaging. These agents are superparamagnetic and consist of a central core of …

EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus

K Overoye-Chan, S Koerner, RJ Looby… - Journal of the …, 2008 - ACS Publications
Thrombus (blood clot) is implicated in a number of life threatening diseases, eg, heart attack,
stroke, pulmonary embolism. EP-2104R is an MRI contrast agent designed to detect …

Emerging concepts in molecular MRI

DE Sosnovik, R Weissleder - Current opinion in biotechnology, 2007 - Elsevier
Molecular magnetic resonance imaging (MRI) offers the potential to image some events at
the cellular and subcellular level and many significant advances have recently been …

Molecular imaging of cardiovascular disease

FA Jaffer, P Libby, R Weissleder - Circulation, 2007 - Am Heart Assoc
sclerosis detection) and myocardial (eg, differentiating endocardium from epicardium)
applications that must also overcome cardiac and respiratory motion and blood flow. In …

In vivo targeting and imaging of atherosclerosis using multifunctional virus-like particles of simian virus 40

X Sun, W Li, X Zhang, M Qi, Z Zhang, XE Zhang… - Nano …, 2016 - ACS Publications
Atherosclerosis is a leading cause of death globally. Targeted imaging and therapeutics are
desirable for the detection and treatment of the disease. In this study, we developed …

Quantitative “magnetic resonance immunohistochemistry” with ligand‐targeted 19F nanoparticles

AM Morawski, PM Winter, X Yu… - … in Medicine: An …, 2004 - Wiley Online Library
Unstable atherosclerotic plaques exhibit microdeposits of fibrin that may indicate the
potential for a future rupture. However, current methods for evaluating the stage of an …