The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

The formation of biofilms is closely associated with persistent and chronic infections, and
physiological heterogeneity such as pH and oxygen gradients renders biofilms highly …

Proximity labeling proteomics (PLP) strategies are powerful approaches to yield snapshots
of protein neighborhoods. Here, we describe a multiscale PLP method with adjustable …

Map** the subcellular organization of proteins is crucial for understanding their biological
functions. Herein, we report a reactive oxygen species induced protein labeling and …

Studying dynamic biological processes requires approaches compatible with the lifetimes of
the biochemical transactions under investigation, which can be very short. We describe a …

Proximity labeling (PL) has emerged as a powerful approach to elucidate proteomes within
a defined radius around a protein of interest (POI). In PL, a catalyst is attached to the POI …

State-of-the-art methods in photoproximity labeling center on the targeted generation and
capture of short-lived reactive intermediates to provide a snapshot of local protein …